Home LiteratureArticle Details
PMID: 3029423 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Course and extent of variation of equine infectious anemia virus during parallel persistent infections.

Journal of virology ·Vol. 61 ·No. 4 ·1987-04-00 ·Pages 1266-70

Payne SL, Salinovich O, Nauman SM, Issel CJ, Montelaro RC

Abstract

Comparisons of peptide and oligonucleotide maps of glycoproteins and RNA from nine isolates of equine infectious anemia virus (EIAV) that were generated during parallel infections of two Shetland ponies revealed that each isolate was structurally unique. Each EIAV isolate contained a unique subset of variant peptides, oligonucleotides, or both, indicating that structural variation in EIAV is a random and noncumulative process and that a large spectrum of possible EIAV variants can be generated in infected animals.

MeSH Terms
Animals Equine Infectious Anemia/microbiology Genetic Variation Horses Infectious Anemia Virus, Equine/genetics Peptide Fragments/analysis Trypsin Viral Envelope Proteins/genetics,isolation & purification
Chemicals
Peptide Fragments Viral Envelope Proteins Trypsin
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Payne S L
Salinovich O
Nauman S M
Issel C J
Montelaro R C
References (18)
18 references, click to expand
  1. Antigenic drift of equine infectious anemia virus in chronically infected horses.
    Arch Gesamte Virusforsch. 1973;41(1):1-10 PMID: 4123810
  2. Comparison of glycoproteins by two-dimensional mapping of glycosylated peptides.
    Anal Biochem. 1986 Aug 15;157(1):19-27 PMID: 3021020
  3. Genomic changes associated with antigenic variation of visna virus durig persistent infection.
    Proc Natl Acad Sci U S A. 1980 Aug;77(8):4454-8 PMID: 6254026
  4. Equine infectious anemia virus, a putative lentivirus, contains polypeptides analogous to prototype-C oncornaviruses.
    Virology. 1980 Dec;107(2):520-5 PMID: 6256947
  5. Isolation and comparative biochemical properties of the major internal polypeptides of equine infectious anemia virus.
    J Virol. 1982 Jun;42(3):1029-38 PMID: 6178843
  6. Genomic changes associated with antigenic variation of visna virus. II. Common nucleotide sequence changes detected in variants from independent isolations.
    J Mol Biol. 1982 Jul 5;158(3):415-34 PMID: 6182297
  7. Virulence and in vitro growth of a cell-adapted strain of equine infectious anemia virus after serial passage in ponies.
    Am J Vet Res. 1982 Sep;43(9):1556-60 PMID: 6293349
  8. Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS).
    Science. 1983 May 20;220(4599):865-7 PMID: 6601823
  9. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).
    Science. 1983 May 20;220(4599):868-71 PMID: 6189183
  10. Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS.
    Science. 1984 May 4;224(4648):497-500 PMID: 6200935
  11. Genomic alterations associated with persistent infections by equine infectious anaemia virus, a retrovirus.
    J Gen Virol. 1984 Aug;65 ( Pt 8):1395-9 PMID: 6086822
  12. Antigenic variation during persistent infection by equine infectious anemia virus, a retrovirus.
    J Biol Chem. 1984 Aug 25;259(16):10539-44 PMID: 6206055
  13. Genomic diversity of human T-lymphotropic virus type III (HTLV-III).
    Science. 1985 Aug 23;229(4715):759-62 PMID: 2992084
  14. Rapid emergence of novel antigenic and genetic variants of equine infectious anemia virus during persistent infection.
    J Virol. 1986 Jan;57(1):71-80 PMID: 3001367
  15. Genetic variation in HTLV-III/LAV over time in patients with AIDS or at risk for AIDS.
    Science. 1986 Jun 20;232(4757):1548-53 PMID: 3012778
  16. Genetic variability of the AIDS virus: nucleotide sequence analysis of two isolates from African patients.
    Cell. 1986 Jul 4;46(1):63-74 PMID: 2424612
  17. Pathogenesis of lentivirus infections.
    Nature. 1986 Jul 10-16;322(6075):130-6 PMID: 2425264
  18. Equine infectious anemia: current knowledge.
    J Am Vet Med Assoc. 1979 Apr 1;174(7):727-33 PMID: 218920
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.61.4.1266-1270.1987
Published
1987-04-00
Pages
1266-70
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC254092
Subset
IM
Grants
NCI NIH HHS · CA-38851 · United States
External Links
PubMed source DOI: 10.1128/JVI.61.4.1266-1270.1987 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2