Home LiteratureArticle Details
PMID: 3033017 Published · ppublish English Case Reports Journal Article

Application of whole-cell DNA restriction endonuclease profiles to the epidemiology of Clostridium difficile-induced diarrhea.

Journal of clinical microbiology ·Vol. 25 ·No. 4 ·1987-04-00 ·Pages 751-3

Kuijper EJ, Oudbier JH, Stuifbergen WN, Jansz A, Zanen HC

Abstract

Two patients in one hospital room acquired pseudomembranous colitis, one shortly after the other. The DNA restriction patterns of isolates from the patients and of four isolates from the environment were indistinguishable from one another and differed from isolates of other patients. Restriction endonuclease digest analysis appears to be a useful method for studying the epidemiology of Clostridium difficile.

MeSH Terms
Clostridium/genetics Cross Infection/microbiology,transmission DNA Restriction Enzymes DNA, Bacterial/analysis Deoxyribonuclease HindIII Electrophoresis, Polyacrylamide Gel Enterocolitis, Pseudomembranous/microbiology,transmission Female Humans Immunologic Techniques Middle Aged
Chemicals
DNA, Bacterial DNA Restriction Enzymes Deoxyribonuclease HindIII
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Kuijper E J
Oudbier J H
Stuifbergen W N
Jansz A
Zanen H C
References (19)
19 references, click to expand
  1. [Postantibiotic pseudomembranous colitis and related forms of diarrhea following use of antibiotics. II. Microbiological aspects].
    Ned Tijdschr Geneeskd. 1979 Dec 29;123(52):2212-7 PMID: 545159
  2. [Is pseudomembranous colitis contagious?].
    Ned Tijdschr Geneeskd. 1986 Oct 4;130(40):1805-7 PMID: 3774036
  3. Is pseudomembranous colitis infectious?
    Lancet. 1981 Feb 14;1(8216):371-2 PMID: 6109999
  4. Epidemiology of antibiotic-associated colitis; isolation of Clostridium difficile from the hospital environment.
    Am J Med. 1981 Apr;70(4):906-8 PMID: 7211925
  5. Isolation of Clostridium difficile from the environment and contacts of patients with antibiotic-associated colitis.
    J Infect Dis. 1981 Jan;143(1):42-50 PMID: 7217711
  6. Clostridium difficile and the aetiology of pseudomembranous colitis.
    Lancet. 1978 May 20;1(8073):1063-6 PMID: 77366
  7. Clostridium difficile: the epidemiology and prevention of hospital-acquired infection.
    Infection. 1982;10(4):203-4 PMID: 7129641
  8. Isolation of Clostridium difficile from patients and the environment of hospital wards.
    J Clin Pathol. 1983 Jan;36(1):88-92 PMID: 6822682
  9. Bacteriophage and bacteriocin typing scheme for Clostridium difficile.
    J Clin Microbiol. 1983 Jun;17(6):1148-52 PMID: 6874905
  10. [Clostridium difficile and antibiotic-associated colitis in risk patients: 2-month epidemiologic study in an intensive care unit].
    Klin Wochenschr. 1983 Nov 2;61(21):1081-7 PMID: 6358656
  11. Typing scheme for Clostridium difficile: its application in clinical and epidemiological studies.
    Lancet. 1984 Apr 28;1(8383):935-8 PMID: 6143871
  12. Polyacrylamide gel electrophoresis patterns produced by Clostridium difficile.
    Rev Infect Dis. 1984 Mar-Apr;6 Suppl 1:S229-34 PMID: 6718936
  13. Immunochemical fingerprinting of Clostridium difficile strains isolated from an outbreak of antibiotic-associated colitis and diarrhoea.
    J Med Microbiol. 1984 Jun;17(3):317-24 PMID: 6726785
  14. Molecular epidemiology of bacterial infections.
    Clin Lab Med. 1985 Sep;5(3):437-45 PMID: 3930133
  15. The epidemiology of Clostridium difficile with use of a typing scheme: nosocomial acquisition and cross-infection among immunocompromised patients.
    J Infect Dis. 1986 Jan;153(1):159-62 PMID: 3941281
  16. Clostridium difficile-associated diarrhea and colitis in adults. A prospective case-controlled epidemiologic study.
    Arch Intern Med. 1986 Jan;146(1):95-100 PMID: 3942469
  17. Is Clostridium difficile endemic in chronic-care facilities?
    Lancet. 1986 Jul 5;2(8497):11-3 PMID: 2873315
  18. Application of a technique for serogrouping Clostridium difficile in an outbreak of antibiotic-associated diarrhoea.
    J Infect. 1986 Jul;13(1):5-9 PMID: 3734468
  19. Antibiotic-associated pseudomembranous colitis.
    Rev Infect Dis. 1979 May-Jun;1(3):530-9 PMID: 399365
Article Info
Journal
Journal of clinical microbiology
Abbr.
J Clin Microbiol
ISSN
0095-1137
DOI
10.1128/jcm.25.4.751-753.1987
Published
1987-04-00
Pages
751-3
Language
English
Region
United States
NLM ID
7505564
PMCID
PMC266078
Subset
IM
External Links
PubMed source DOI: 10.1128/jcm.25.4.751-753.1987 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2