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PMID: 3044459 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S. Review

Amino acid transport systems of lysosomes: possible substitute utility of a surviving transport system for one congenitally defective or absent.

Bioscience reports ·Vol. 8 ·No. 2 ·1988-04-00 ·Pages 121-9

Christensen HN

Abstract

Ways in which other transport systems may compensate for one that is genetically defective are considered. Comparisons of the transport systems of organelles (here the lysosome) with the transport system at the plasma membrane has significant implications for chemotherapy.

MeSH Terms
Amino Acid Metabolism, Inborn Errors/therapy Amino Acids/metabolism Biological Transport Cell Membrane/metabolism Cystine/metabolism Humans Intracellular Membranes/metabolism Lysosomes/metabolism
Chemicals
Amino Acids Cystine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Christensen H N
Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor 48109.
Article Info
Journal
Bioscience reports
Abbr.
Biosci Rep
ISSN
0144-8463
DOI
10.1007/BF01116456
Published
1988-04-00
Pages
121-9
Language
English
Region
England
NLM ID
8102797
Subset
IM
Grants
NIDDK NIH HHS · DK32281 · United States
NICHD NIH HHS · HD01233 · United States
External Links
PubMed source DOI: 10.1007/BF01116456 View journal details
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