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PMID: 3063399 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The glucose-and ethanol-dependent regulation of PDC1 from Saccharomyces cerevisiae are controlled by two distinct promoter regions.

Current genetics ·Vol. 14 ·No. 4 ·1988-10-00 ·Pages 337-44

Kellermann E, Hollenberg CP

Abstract

A 870 bp promoter fragment of the PDC1 gene that includes the carbon source dependent regulatory regions was investigated using 5' and 3' promoter deletions. The results indicate that glucose and ethanol regulation of PDC1 transcription are independently controlled by distinct cis-acting regions. The consensus sequence AAATCGATA may play a role in this regulation, while the sequence (ATCA)AACCT may be important in transcription initiation.

MeSH Terms
Amino Acid Sequence Base Sequence Carboxy-Lyases/genetics Ethanol/physiology Genes, Fungal Glucose/physiology Immunoblotting Molecular Sequence Data Plasmids Promoter Regions, Genetic Pyruvate Decarboxylase/genetics Regulatory Sequences, Nucleic Acid Saccharomyces cerevisiae/enzymology,genetics Transformation, Genetic beta-Lactamases/genetics
Chemicals
Ethanol beta-Lactamases Carboxy-Lyases Pyruvate Decarboxylase Glucose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kellermann E
Institut für Mikrobiologie, Universität Düsseldorf, Federal Republic of Germany.
Hollenberg C P
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Article Info
Journal
Current genetics
Abbr.
Curr Genet
ISSN
0172-8083
DOI
10.1007/BF00419991
Published
1988-10-00
Pages
337-44
Language
English
Region
United States
NLM ID
8004904
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00419991 View journal details
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