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PMID: 30747461 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Reconciling PC-MRI and CFD: An in-vitro study.

NMR in biomedicine ·Vol. 32 ·No. 5 ·2019-00-00 ·页码 e4063

Puiseux T, Sewonu A, Meyrignac O, Rousseau H, Nicoud F, Mendez S, Moreno R

Abstract

Several well-resolved 4D Flow MRI acquisitions of an idealized rigid flow phantom featuring an aneurysm, a curved channel as well as a bifurcation were performed under pulsatile regime. The resulting hemodynamics were processed to remove MRI artifacts. Subsequently, they were compared with CFD predictions computed on the same flow domain, using an in-house high-order low dissipative flow solver. Results show that reaching a good agreement is not straightforward but requires proper treatments of both techniques. Several sources of discrepancies are highlighted and their impact on the final correlation evaluated. While a very poor correlation (r2  = 0.63) is found in the entire domain between raw MRI and CFD data, correlation as high as r2  = 0.97 is found when artifacts are removed by post-processing the MR data and down sampling the CFD results to match the MRI spatial and temporal resolutions. This work demonstrates that, in a well-controlled environment, both PC-MRI and CFD might bring reliable and correlated flow quantities when a proper methodology to reduce the errors is followed.

Keywords
cardiovascular blood flows computational fluid dynamics large eddy simulation phase contrast magnetic resonance imaging validation work flow
MeSH 主题词
Hydrodynamics Magnetic Resonance Imaging/methods Phantoms, Imaging Regional Blood Flow Stress, Mechanical Systole/physiology Time Factors
作者与单位
共 7 位作者,点击展开单位 / ORCID
Puiseux Thomas ORCID
IMAG, Univ Montpellier, CNRS, Montpellier, France. | ALARA Expertise, Strasbourg, France.
Sewonu Anou
ALARA Expertise, Strasbourg, France. | I2MC, INSERM U1048, Toulouse, France.
Meyrignac Olivier
I2MC, INSERM U1048, Toulouse, France. | Department of Radiology, CHU de Toulouse, Toulouse, France.
Rousseau Hervé
I2MC, INSERM U1048, Toulouse, France. | Department of Radiology, CHU de Toulouse, Toulouse, France.
Nicoud Franck
IMAG, Univ Montpellier, CNRS, Montpellier, France.
Mendez Simon
IMAG, Univ Montpellier, CNRS, Montpellier, France.
Moreno Ramiro
ALARA Expertise, Strasbourg, France. | I2MC, INSERM U1048, Toulouse, France.
Article Info
Journal
NMR in biomedicine
Abbr.
NMR Biomed
ISSN
1099-1492
Published
2019-00-00
电子出版
2019-00-12
页码
e4063
Language
English
Country/Region
England
NLM ID
8915233
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