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PMID: 3080910 Published · ppublish English Comparative Study Journal Article

Polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in human milk: effects of maternal factors and previous lactation.

American journal of public health ·Vol. 76 ·No. 2 ·1986-02-00 ·Pages 172-7

Rogan WJ, Gladen BC, McKinney JD, Carreras N, Hardy P, Thullen J, Tingelstad J, Tully M

Abstract

The authors measured polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in maternal serum, cord blood, placenta, and serial samples of breast milk from 868 women. Almost all samples of breast milk showed detectable levels of both chemicals. Overall, values for DDE in this study are within the range of those found previously, whereas those for PCBs are somewhat higher. Possible causes of variation in levels were investigated. For DDE, older women, Black women, cigarette smokers, and women who consumed sport fish during pregnancy had higher levels; only age and race showed large effects. For PCBs, older women, women who regularly drink alcohol, and primiparae had higher levels. In addition, both chemicals showed modest variation across occupational groupings. Casual exposure to a PCB spill did not result in chemical levels different from background. In general, women have higher levels in their first lactation and in the earlier samples of a given lactation, and levels decline both with time spent breast-feeding and with number of children nursed. These striking declines are presumably a measure of exposure to the child.

MeSH Terms
Adolescent Adult African Americans Breast Feeding Child, Preschool Colostrum/analysis Dichlorodiphenyl Dichloroethylene/analysis,blood Female Fetal Blood/analysis Food Contamination Humans Infant Infant, Newborn Lactation Maternal Age Milk, Human/analysis North Carolina Placenta/analysis Polychlorinated Biphenyls/analysis,blood Pregnancy Smoking
Chemicals
Dichlorodiphenyl Dichloroethylene Polychlorinated Biphenyls
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Rogan W J
Gladen B C
McKinney J D
Carreras N
Hardy P
Thullen J
Tingelstad J
Tully M
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Article Info
Journal
American journal of public health
Abbr.
Am J Public Health
ISSN
0090-0036
DOI
10.2105/ajph.76.2.172
Published
1986-02-00
Pages
172-7
Language
English
Region
United States
NLM ID
1254074
PMCID
PMC1646471
Subset
IM
External Links
PubMed source DOI: 10.2105/ajph.76.2.172 PMC Full Text View journal details
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