Home LiteratureArticle Details
PMID: 3099793 Published · ppublish English Journal Article

Self assembly of microtubule associated protein tau into filaments resembling those found in Alzheimer disease.

Biochemical and biophysical research communications ·Vol. 141 ·No. 2 ·1986-12-15 ·Pages 790-6

Montejo de Garcini E, Serrano L, Avila J

Abstract

Microtubule associated protein tau factor self-assembles into filamentous structures resembling the paired helical filaments found in Alzheimer disease. Tau polymerization requires of a previous modification; conversion of glutamine into glutamic acid by deamination.

MeSH Terms
Alzheimer Disease/pathology Animals Glutamates/metabolism Glutaminase/metabolism Glutamine/metabolism Macromolecular Substances Microtubule-Associated Proteins/metabolism Neurofibrils/ultrastructure Peptide Fragments/analysis Polymers Protein Binding Swine tau Proteins
Chemicals
Glutamates Macromolecular Substances Microtubule-Associated Proteins Peptide Fragments Polymers tau Proteins Glutamine Glutaminase
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Montejo de Garcini E
Serrano L
Avila J
Article Info
Journal
Biochemical and biophysical research communications
Abbr.
Biochem Biophys Res Commun
ISSN
0006-291X
DOI
10.1016/s0006-291x(86)80242-x
Published
1986-12-15
Pages
790-6
Language
English
Region
United States
NLM ID
0372516
Subset
IM
External Links
PubMed source DOI: 10.1016/s0006-291x(86)80242-x View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2