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PMID: 3113331 Published · ppublish English Clinical Trial Controlled Clinical Trial Journal Article Research Support, Non-U.S. Gov't

Effect of ciprofloxacin on carrier rate of Neisseria meningitidis in army recruits in Finland.

Antimicrobial agents and chemotherapy ·Vol. 31 ·No. 6 ·1987-06-00 ·Pages 962-3

Renkonen OV, Sivonen A, Visakorpi R

Abstract

The efficacy of ciprofloxacin in eradicating pharyngeal colonization of Neisseria meningitidis was studied among army recruits in Finland. Ciprofloxacin (250 mg) or placebo was given twice a day for 2 days to 118 meningococcal carriers. Meningococcal carriage was eradicated in 96% of subjects given ciprofloxacin and in 13% of those given placebos.

MeSH Terms
Carrier State/drug therapy,microbiology Ciprofloxacin/therapeutic use Finland Humans Male Microbial Sensitivity Tests Military Personnel Neisseria meningitidis/drug effects Pharynx/microbiology
Chemicals
Ciprofloxacin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Renkonen O V
Sivonen A
Visakorpi R
References (9)
9 references, click to expand
  1. An epidemic due to sulphonamide-resistant group A meningococci in the Helsinki area (Finland). Epidemiological and clinical observations.
    Scand J Infect Dis. 1976;8(4):249-54 PMID: 827013
  2. Neisseria meningitidis infections in Northern Norway: an epidemic in 1974-1975 due mainly to group B organisms.
    J Infect Dis. 1977 Apr;135(4):669-72 PMID: 404365
  3. Use of antiserum agar plates for serogrouping of meningococci.
    J Clin Pathol. 1977 Sep;30(9):834-7 PMID: 410847
  4. The effect of chemoprophylactic use of rifampin and minocycline on rates of carriage of Neisseria meningitidis in army recruits in Finland.
    J Infect Dis. 1978 Mar;137(3):238-44 PMID: 416147
  5. Comparative in vitro studies with 4-quinolone antimicrobials.
    Drugs Exp Clin Res. 1985;11(5):317-29 PMID: 2941259
  6. Adverse effects of two rifampicin dosage regimens for the prevention of meningococcal infection.
    Lancet. 1984 Jan 14;1(8368):101-2 PMID: 6140395
  7. Antibacterial activities of ciprofloxacin, norfloxacin, oxolinic acid, cinoxacin, and nalidixic acid.
    Antimicrob Agents Chemother. 1984 May;25(5):633-7 PMID: 6233935
  8. Multiple-dose pharmacokinetics and safety of ciprofloxacin in normal volunteers.
    Antimicrob Agents Chemother. 1984 Nov;26(5):741-4 PMID: 6517556
  9. Trends in meningococcal disease in the United States, 1975-1980.
    J Infect Dis. 1983 Oct;148(4):754-8 PMID: 6313816
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.31.6.962
Published
1987-06-00
Pages
962-3
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC284224
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.31.6.962 PMC Full Text View journal details
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