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PMID: 31382837 Published · ppublish English Comparative Study Journal Article

Comparison of Fluid Dynamics Variations Between Chimney and Fenestrated Endografts for Pararenal Aneurysms Repair: A Patient Specific Computational Study as Motivation for Clinical Decision-Making.

Vascular and endovascular surgery ·Vol. 53 ·No. 7 ·2019-10-00 ·页码 572-582

Moulakakis KG, Kakisis J, Gonidaki E, Lazaris AM, Tsangaris S, Geroulakos G, Manopoulos C

Abstract

Limited data exist concerning the fluid dynamic changes induced by endovascular aortic repair with fenestrated and chimney graft modalities in pararenal aneurysms. We aimed to investigate and compare the wall shear stress (WSS) and flow dynamics for the branch vessels before and after endovascular aortic repair with fenestrated and chimney techniques. Modeling was done for patient specific pararenal aortic aneurysms employing fenestrated and chimney grafts (Materialise Mimics 10.0) before and after the endovascular procedure, using computed tomography scans of patients. Surface and spatial grids were created using the ANSYS CFD meshing software 2019 R2. Assessment of blood flow, streamlines, and WSS before and after aneurysm repair was performed. The endovascular repair with chimney grafts leaded to a 43% to 53% reduction in perfusion in renal arteries. In fenestrated reconstruction, we observed a 15% reduced perfusion in both renal arteries. In both cases, we observed a decrease in the recirculation phenomena of the aorta after endovascular repair. Concerning the grafts of the renal arteries, we observed in both the transverse and longitudinal axes low WSS regions with simultaneous recirculation of the flow 1 cm distal to the ostium sites in both aortic graft models. High WSS regions appeared in the sites of ostium. We observed reduced renal perfusion in chimney grafts compared to fenestrated grafts, probably caused by the long and kinked characteristics of these devices.

Keywords
aneurysm chimney computational fluid dynamics endovascular repair fenestrated pararenal
MeSH 主题词
Aortic Aneurysm, Abdominal/diagnostic imaging,physiopathology,surgery Aortography/methods Blood Vessel Prosthesis Blood Vessel Prosthesis Implantation/adverse effects,instrumentation Clinical Decision-Making Computed Tomography Angiography Endovascular Procedures/adverse effects,instrumentation Hemodynamics Humans Hydrodynamics Models, Cardiovascular Patient Selection Patient-Specific Modeling Postoperative Complications/diagnostic imaging,etiology,physiopathology Predictive Value of Tests Prosthesis Design Radiographic Image Interpretation, Computer-Assisted Renal Circulation Stress, Mechanical Treatment Outcome
作者与单位
共 7 位作者,点击展开单位 / ORCID
Moulakakis Konstantinos G ORCID
1 Department of Vascular Surgery, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.
Kakisis John
1 Department of Vascular Surgery, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.
Gonidaki Eleni
2 Biofluid Mechanics and Biomedical Engineering Laboratory, Fluids Section, School of Mechanical Engineering, National Technical University of Athens, Greece.
Lazaris Andreas M
1 Department of Vascular Surgery, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.
Tsangaris Sokrates
2 Biofluid Mechanics and Biomedical Engineering Laboratory, Fluids Section, School of Mechanical Engineering, National Technical University of Athens, Greece.
Geroulakos George
1 Department of Vascular Surgery, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.
Manopoulos Christos
2 Biofluid Mechanics and Biomedical Engineering Laboratory, Fluids Section, School of Mechanical Engineering, National Technical University of Athens, Greece.
Article Info
Journal
Vascular and endovascular surgery
Abbr.
Vasc Endovascular Surg
ISSN
1938-9116
Published
2019-10-00
电子出版
2019-00-05
页码
572-582
Language
English
Country/Region
United States
NLM ID
101136421
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