The in-vitro activity of some antimicrobial agents against methicillin-resistant Staphylococcus aureus.

The Journal of antimicrobial chemotherapy ·Vol. 15 ·No. 3 ·1985-03-00 ·Pages 291-5

Moorhouse EC, Mulvihill TE, Jones L, Mooney D, Falkiner FR, Keane CT

Abstract

A total of 185 strains of methicillin resistant Staphylococcus aureus was investigated for sensitivity to five other antimicrobial agents. The vast majority of these strains were also resistant to gentamicin and fusidic acid. Rifampicin was the most active drug tested (MIC90, 0.007 mg/l), while two newer compounds teichomycin and ciprofloxacin showed equal and appreciable activity (MIC90, 0.5 mg/l).

MeSH Terms

Anti-Bacterial Agents/pharmacology Ciprofloxacin Fusidic Acid/pharmacology Gentamicins/pharmacology Glycopeptides/pharmacology Methicillin/pharmacology Microbial Sensitivity Tests Penicillin Resistance Quinolines/pharmacology Rifampin/pharmacology Staphylococcus Phages/classification Staphylococcus aureus/drug effects Teicoplanin Vancomycin/pharmacology

Chemicals

Anti-Bacterial Agents Gentamicins Glycopeptides Quinolines Fusidic Acid Ciprofloxacin Teicoplanin Vancomycin Methicillin Rifampin

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Moorhouse E C

Mulvihill T E

Jones L

Mooney D

Falkiner F R

Keane C T

Article Info

Journal

The Journal of antimicrobial chemotherapy

Abbr.

J Antimicrob Chemother

ISSN

0305-7453

DOI

10.1093/jac/15.3.291

Published

1985-03-00

Pages

291-5

Language

English

Region

England

NLM ID

7513617

Subset

External Links

PubMed source DOI: 10.1093/jac/15.3.291 View journal details

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The in-vitro activity of some antimicrobial agents against methicillin-resistant Staphylococcus aureus.

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