Detection of HIV-1 neutralizing antibodies by a simple, rapid, colorimetric assay.

AIDS research and human retroviruses ·Vol. 4 ·No. 1 ·1988-02-00 ·Pages 63-9

Langlois AJ, Matthews TJ, Weinhold KJ, Chaffee S, Hershfield M, Bolognesi DP

Abstract

A rapid, simple, reproducible and semi-quantitative assay to measure neutralizing antibodies has been developed. It employs a unique cell line which is exquisitively sensitive to infection with all HIV isolates tested. The assay is amenable to microtiter formulation as well as analysis by automation.

MeSH Terms

Antibodies, Viral/analysis Cell Line Colorimetry HIV/immunology HIV Antibodies Humans Neutralization Tests/methods

Chemicals

Antibodies, Viral HIV Antibodies

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Langlois A J

Duke University Medical Center, Department of Surgery, Durham, NC 27710.

Matthews T J

Weinhold K J

Chaffee S

Hershfield M

Bolognesi D P

Article Info

Journal

AIDS research and human retroviruses

Abbr.

AIDS Res Hum Retroviruses

ISSN

0889-2229

DOI

10.1089/aid.1988.4.63

Published

1988-02-00

Pages

63-9

Language

English

Region

United States

NLM ID

8709376

Subset

Corrections

ErratumIn

External Links

PubMed source DOI: 10.1089/aid.1988.4.63 View journal details

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Detection of HIV-1 neutralizing antibodies by a simple, rapid, colorimetric assay.

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