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PMID: 325364 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

A new host gene (groPC) necessary for lambda DNA replication.

Molecular & general genetics : MGG ·Vol. 151 ·No. 1 ·1977-02-28 ·Pages 27-34

Sunshine M, Feiss M, Stuart J, Yochem J

Abstract

The isolation of a bacterial mutation in a gene, designated groPC, which affects the growth of phages lambda and P2 is described. Lambda replication is severely limited in the strain, and some lambda pi mutations, which map in (or near) the P gene, allow growth. The gro mutation, groPC259, is recessive to wild type and maps between threonine (thr) and diaminopimelate (dapB) on the E. coli chromosome. The possibility that the groPC gene is concerned with host DNA replication is discussed.

MeSH Terms
Chromosome Mapping Chromosomes, Bacterial Coliphages/metabolism DNA Replication DNA, Viral/biosynthesis Escherichia coli Genes Mutation Recombination, Genetic Transduction, Genetic
Chemicals
DNA, Viral
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Sunshine M
Feiss M
Stuart J
Yochem J
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28 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00446909
Published
1977-02-28
Pages
27-34
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00446909
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