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PMID: 32592320 Published · ppublish English Journal Article

Outcomes of cats treated with maxillectomy: 60 cases. A Veterinary Society of Surgical Oncology retrospective study.

Veterinary and comparative oncology ·Vol. 19 ·No. 4 ·2021-12-00 ·页码 641-650

Liptak JM, Thatcher GP, Mestrinho LA, Séguin B, Vernier T, Martano M, Husbands BD, Veytsman S, van Nimwegen SA, De Mello Souza CH, Mullins RA, Barry SL, Selmic LE

Abstract

Maxillectomy is poorly described for the management of oral tumours in cats and is occasionally not recommended because of the high complication rate and sub-optimal outcome reported in cats treated with mandibulectomy. The purpose of this study was to retrospectively evaluate the complications and oncologic outcome in cats treated with maxillectomy. Sixty cats were included in the study. Maxillectomy procedures included unilateral rostral (20.0%), bilateral rostral (23.3%), segmental (10.0%), caudal (20.0%) and total unilateral maxillectomy (26.7%). Intra-operative and post-operative complications were reported in 10 (16.7%) and 34 (56.7%) cats, respectively. The most common post-operative complications were hyporexia (20.0%) and incisional dehiscence (20.0%). The median duration of hyporexia was 7 days. Benign tumours were diagnosed in 19 cats (31.7%) and malignant tumours in 41 cats (68.3%). Local recurrence and metastatic rates were 18.3% and 4.9%, respectively; the median progression-free interval (PFI) was not reached. The disease-related median survival time was not reached overall or for either benign or malignant tumours. The 1- and 2-year survival rates were, respectively, 100% and 79% for cats with benign tumours, 89% and 89% for cats with malignant tumours, 94% and 94% for cats with fibrosarcomas, 83% and 83% for cats with squamous cell carcinomas, and 80% and 80% for cats with osteosarcomas. Poor prognostic factors included mitotic index for PFI, adjuvant chemotherapy for both PFI and survival time, and local recurrence for survival time. Maxillectomy is a viable treatment option for cats resulting in good local tumour control and long survival times.

Keywords
complications fibrosarcoma oral tumour osteosarcoma squamous cell carcinoma
作者与单位
共 13 位作者,点击展开单位 / ORCID
Liptak Julius M ORCID
VCA Canada-Alta Vista Animal Hospital, Ottawa, Ontario, Canada.
Thatcher Graham P
VCA Canada-Alta Vista Animal Hospital, Ottawa, Ontario, Canada. | Department of Veterinary Clinical Science, College of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, USA.
Mestrinho Lisa A ORCID
CIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, Lisbon, Portugal.
Séguin Bernard ORCID
Flint Animal Cancer Center, Colorado State University, Fort Collins, Colorado, USA.
Vernier Timothy
Flint Animal Cancer Center, Colorado State University, Fort Collins, Colorado, USA.
Martano Marina
Department of Veterinary Medical Sciences, University of Parma, Parma, Italy.
Husbands Brian D
Veterinary Medical Center, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Veytsman Stan
Veterinary Medical Center, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
van Nimwegen Sebastiaan A
Department of Clinical Sciences of Companion Animals, Utrecht University, Utrecht, Netherlands.
De Mello Souza Carlos H ORCID
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
Mullins Ronan A
Section of Veterinary Clinical Sciences, University College Dublin, Belfield, Ireland.
Barry Sabrina L
Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
Selmic Laura E ORCID
Department of Veterinary Clinical Science, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
Article Info
Journal
Veterinary and comparative oncology
Abbr.
Vet Comp Oncol
ISSN
1476-5829
Published
2021-12-00
电子出版
2020-00-16
页码
641-650
Language
English
Country/Region
England
NLM ID
101185242
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