Somatotrophs in the human fetal anterior pituitary. An electron microscopic-immunocytochemical study.
An immunocytochemical staining of ultrathin sections using the peroxidase-antiperoxidase complex was employed to localize the somatotrophs in the anterior pituitary of the human fetus. This technique allowed a specific identification of the somatotrophs and a detailed description of their ultrastructure which was well preserved by the fixation employed. They appeared as cells with a dense cytoplasmic matrix, lamellar rough endoplasmic reticulum, and prominent Golgi apparatus. Their secretory granules had a mean diameter of 300 nm.
15 references, click to expand
-
Characterization of human growth hormone preparations used for the treatment of pituitary dwarfism: a comparison of concurrently used batches.J Clin Endocrinol Metab. 1975 May;40(5):856-62 PMID: 1127091
-
[Ultrastructure of granulated cells of the fetal rat pituitary gland; identification of corticotrophic and thyreotrophic cells].Arch Anat Microsc Morphol Exp. 1973 Apr-Jun;62(2):185-206 PMID: 4787181
-
Ultrastructure of the fetal rat adenohypophysis.Acta Endocrinol Suppl (Copenh). 1974;188:1-113 PMID: 4366046
-
[Observation by electron microscopy of the anterior lobe of the human embryonal pituitary in the 3d month of intrauterine life].C R Seances Soc Biol Fil. 1965;159(7):1574-6 PMID: 4221667
-
Immunocytochemistry of acidophil granules of human pituitary.Arch Neurol. 1969 Jun;20(6):634-43 PMID: 4306019
-
The cellular localisation of growth hormone in the human foetal adenohypophysis.J Pathol Bacteriol. 1966 Jul;92(1):179-83 PMID: 4163179
-
Electron microscopic study of the adrenocorticotropin-producing cell with the use of unlabeled antibody and the soluble peroxidase-antiperoxidase complex.J Histochem Cytochem. 1972 Aug;20(8):590-603 PMID: 4114593
-
Application of peroxidase-labelled antibodies to the intracellular localization of hormones.Acta Endocrinol Suppl (Copenh). 1971;153:190-204 PMID: 4325484
-
Growth hormone in human fetal pituitary glands and cord blood.J Clin Endocrinol Metab. 1971 Dec;33(6):908-11 PMID: 5135631
-
Nongranulated cells in the mouse adenohypophysis.Z Zellforsch Mikrosk Anat. 1972;124(3):387-405 PMID: 5011358
-
[Human pituitary prolactin: radioimmunologic detection and level during pregnancy].Ann Endocrinol (Paris). 1972 Jul-Aug;33(4):357-60 PMID: 4664000
-
Adenohypophysis: ultrastructural cytochemistry. A review.J Histochem Cytochem. 1973 Oct;21(10):855-94 PMID: 4356692
-
The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes.J Histochem Cytochem. 1970 May;18(5):315-33 PMID: 4192899
-
The ontogenesis of human fetal hormones. I. Growth hormone and insulin.J Clin Invest. 1972 Dec;51(12):3080-93 PMID: 4674397
-
Electron microscopic studies of the anterior pituitaries and adrenal cortices of normal and anencephalic human fetuses.J Electron Microsc (Tokyo). 1972;21(1):29-39 PMID: 4342819
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