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PMID: 334742 Published · ppublish English Journal Article

Regulation of aromatic amino acid transport systems in Escherichia coli K-12.

Journal of bacteriology ·Vol. 132 ·No. 2 ·1977-11-00 ·Pages 453-61

Whipp MJ, Pittard AJ

Abstract

The regulation of the aromatic amino acid transport systems was investigated. The common (general) aromatic transport system and the tyrosine-specific transport system were found to be subject to repression control, thus confirming earlier reports. In addition, tryosine- and tryptophan-specific transport were found to be enhanced by growth of cells with phenylalanine. The repression and enhancement of the transport systems was abolished in a strain carrying an amber mutation in the regulator gene tyrR. This indicates that the tyrR gene product, which was previously shown to be involved in regulation of aromatic biosynthetic enzymes, is also involved in the regulation of the aromatic amino acid transport systems.

MeSH Terms
Amino Acids/genetics,metabolism Biological Transport, Active Enzyme Repression Escherichia coli/genetics,metabolism Genes, Regulator Glucose/metabolism Mutation Phenylalanine/metabolism Tryptophan/metabolism Tyrosine/metabolism
Chemicals
Amino Acids Tyrosine Phenylalanine Tryptophan Glucose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Whipp M J
Pittard A J
References (20)
20 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.132.2.453-461.1977
Published
1977-11-00
Pages
453-61
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC221884
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.132.2.453-461.1977 PMC Full Text View journal details
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