Limiting factors in bacterial phagocytosis by human polymorphonuclear leukocytes.

Acta pathologica et microbiologica Scandinavica. Section C, Immunology ·Vol. 85 ·No. 5 ·1977-10-00 ·Pages 345-9

Björkstén B, Peterson PK, Verhoef J, Quie PG

Abstract

Limiting factors in neutrophil phagocytosis were studied using a sensitive assay by which attachment, ingestion and intracellular killing of bacteria could be separated. Phagocytosis was found to be limited by the attachment capacity of neutrophils. Ingestion and intracellular killing proceeded at a constant rate proportional to the number of bacteria attached to the neutrophils.

MeSH Terms

Bacteria Escherichia coli Humans Neutrophils/immunology Phagocytosis Polymorphism, Genetic Staphylococcus Staphylococcus aureus Streptococcus

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Björkstén B

Peterson P K

Verhoef J

Quie P G

Article Info

Journal

Acta pathologica et microbiologica Scandinavica. Section C, Immunology

Abbr.

Acta Pathol Microbiol Scand C

ISSN

0304-1328

DOI

10.1111/j.1699-0463.1977.tb03652.x

Published

1977-10-00

Pages

345-9

Language

English

Region

Denmark

NLM ID

7508469

Subset

External Links

PubMed source DOI: 10.1111/j.1699-0463.1977.tb03652.x

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