Antibody response of patients against a 120 kDa surface protein of Campylobacter pylori.

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology ·Vol. 268 ·No. 2 ·1988-04-00 ·Pages 271-6

Apel I, Jacobs E, Kist M, Bredt W

Abstract

Campylobacter pylori strains were isolated and serum samples were obtained from 63 patients. Immunoblots of 52 patients sera using their own isolates as antigen showed a 120 kDa band, which was missing in the other 11 isolates and the respective sera. This band was not detected in other Campylobacter species. Effects of trypsin treatment of bacteria and absorption of sera by live organisms suggest a C. pylori-specific surface protein.

MeSH Terms

Antibodies, Bacterial/biosynthesis Antigens, Bacterial/immunology Antigens, Surface/immunology Campylobacter/immunology Campylobacter Infections/immunology Humans Immunoassay Immunoglobulin A/biosynthesis Immunoglobulin G/biosynthesis Immunoglobulin M/biosynthesis Immunoglobulins/biosynthesis

Chemicals

Antibodies, Bacterial Antigens, Bacterial Antigens, Surface Immunoglobulin A Immunoglobulin G Immunoglobulin M Immunoglobulins

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Apel I

Abteilung Mikrobiologie und Hygiene, Klinikum der Universität Freiburg.

Jacobs E

Kist M

Bredt W

Article Info

Journal

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology

Abbr.

Zentralbl Bakteriol Mikrobiol Hyg A

ISSN

0176-6724

DOI

10.1016/s0176-6724(88)80012-9

Published

1988-04-00

Pages

271-6

Language

English

Region

Germany

NLM ID

8403032

Subset

External Links

PubMed source DOI: 10.1016/s0176-6724(88)80012-9

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Antibody response of patients against a 120 kDa surface protein of Campylobacter pylori.

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