Home LiteratureArticle Details
PMID: 3400644 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Consanguineous marriage and reproduction in Beirut, Lebanon.

American journal of human genetics ·Vol. 43 ·No. 2 ·1988-08-00 ·Pages 188-96

Khlat M

Abstract

Effects of consanguineous marriages on couples' fertility and on offspring mortality were investigated in Beirut through a population-based health survey of 2,752 households. A multistage random sampling procedure was used, and information was obtained from all ever-married women in the household about their reproductive performance and genealogical relationship with spouse; demographic and socioeconomic information was also recorded. Twenty-five percent of all marriages were between relatives, and the spouses were first cousins in approximately 57% of all consanguineous marriages. Total pregnancies, live births, and living children were significantly higher among consanguineous couples than among nonconsanguineous ones, as was the proportion dead among children ever born. However, no difference remained in either fertility or mortality, when allowance was made for socioeconomic status, religious affiliation, and marriage duration. The issue of confounding is discussed, and the lack of significant pattern in the final analysis is interpreted as resulting from a long-term practice of consanguineous marriages.

MeSH Terms
Adult Christianity Consanguinity Demography Female Fertility Humans Islam Lebanon Marriage Maternal Age Mortality Reproduction Socioeconomic Factors
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Khlat M
Faculty of Health Sciences, American University of Beirut.
References (29)
29 references, click to expand
  1. Childhood mortality estimated from reports on previous births given by mothers at the time of a maternity: II. Adapted multiplying factor technique.
    Asian Pac Cens Forum. 1985 May;11(4):5-9 PMID: 12267277
  2. Inbreeding and prereproductive mortality in the Old Order Amish. III. Direct and indirect effects of inbreeding.
    Am J Epidemiol. 1987 Mar;125(3):473-83 PMID: 3812453
  3. The effects of parental consanguinity and inbreeding in Hirado, Japan. I. Stillbirths and prereproductive mortality.
    Am J Hum Genet. 1970 May;22(3):239-62 PMID: 5462919
  4. The effect of parental consanguinity and inbreeding in Hirado, Japan. IV. Fertility and reproductive compensation.
    Humangenetik. 1970;9(4):294-315 PMID: 5449944
  5. The effects of parental consanguinity and inbreeding in Hirado, Japan. V. Summary and interpretation.
    Am J Hum Genet. 1972 Jul;24(4):425-53 PMID: 5031982
  6. Some effects on the offspring of uncle-niece marriage in the Moroccan Jewish community in Jerusalem.
    Am J Hum Genet. 1974 Jan;26(1):65-72 PMID: 4811756
  7. Amenorrhea, intrauterine mortality and parental consanguinity in an isolated French Canadian population.
    Hum Biol. 1974 Sep;46(3):405-24 PMID: 4426601
  8. The mutation load in an African population. I. An analysis of consanguineous marriages in Nigeria.
    Am J Hum Genet. 1974 Nov;26(6):674-82 PMID: 4474815
  9. Effects of consanguineous marriage and inbreeding on couple fertility and offspring mortality in rural Sri Lanka.
    Hum Biol. 1976 Feb;48(1):139-46 PMID: 1254281
  10. Inbreeding effects on human reproduction in Tamil Nadu of South India.
    Ann Hum Genet. 1977 Jul;41(1):87-98 PMID: 921221
  11. Survey on the effects of inbreeding in two populations of Bihar.
    Indian J Med Res. 1978 Aug;68:295-9 PMID: 721202
  12. Congenital abnormalities in newborns of consanguineous and nonconsanguineous parents.
    Obstet Gynecol. 1979 Feb;53(2):195-9 PMID: 570260
  13. Inbreeding effects in a coastal village and other parts of Andhra Pradesh.
    Acta Genet Med Gemellol (Roma). 1978;27:89-93 PMID: 751385
  14. Effect of reproductive compensation and the desire to have male offspring on the incidence of a sex-linked lethal disease.
    Am J Hum Genet. 1980 Jul;32(4):575-81 PMID: 7395870
  15. Genetic diseases in Lebanon.
    Am J Med Genet. 1980;7(2):187-203 PMID: 7468647
  16. Consanguinity, fecundity and post-natal mortality in Karnataka, South India.
    Ann Hum Biol. 1981 Sep-Oct;8(5):469-72 PMID: 7294724
  17. Reproductive wastage and developmental disorders in relation to consanguinity in south India.
    Trop Geogr Med. 1981 Sep;33(3):275-80 PMID: 7314241
  18. A review of goodness of fit statistics for use in the development of logistic regression models.
    Am J Epidemiol. 1982 Jan;115(1):92-106 PMID: 7055134
  19. Consanguinity and inbreeding effects on fertility, mortality and morbidity in the Malas of Chittoor district.
    Z Morphol Anthropol. 1983;74(1):45-51 PMID: 6858305
  20. Cousin marriages in Beirut, Lebanon: is the pattern changing?
    J Biosoc Sci. 1984 Jul;16(3):369-73 PMID: 6470019
  21. [Consanguinity and public health. Algerian study].
    Arch Fr Pediatr. 1984 Jun-Jul;41(6):435-40 PMID: 6487047
  22. Effects of inbreeding on mortality: a study among three South Indian communities.
    Hum Biol. 1985 Feb;57(1):47-59 PMID: 3988270
  23. Inbreeding and fertility in a South Indian population.
    Ann Hum Biol. 1985 May-Jun;12(3):267-74 PMID: 4015035
  24. The effect of consanguineous marriages on reproductive wastage.
    Clin Genet. 1986 May;29(5):384-8 PMID: 3742845
  25. Perception of consanguineous marriages and their genetic effects among a sample of couples from Beirut.
    Am J Med Genet. 1986 Oct;25(2):299-306 PMID: 3777026
  26. Modernization and consanguineous marriage in Beirut.
    J Biosoc Sci. 1986 Oct;18(4):489-95 PMID: 3782199
  27. An epidemiologic approach to the evaluation of the effect of inbreeding on prereproductive mortality.
    Am J Epidemiol. 1987 Feb;125(2):251-62 PMID: 3544816
  28. Inbreeding and prereproductive mortality in the Old Order Amish. I. Genealogic epidemiology of inbreeding.
    Am J Epidemiol. 1987 Mar;125(3):453-61 PMID: 3812451
  29. Mortality among offspring of consanguineous marriage in a rural area of East Jordan.
    J Trop Pediatr Afr Child Health. 1966 Mar;11(4):95-9 PMID: 5299361
Article Info
Journal
American journal of human genetics
Abbr.
Am J Hum Genet
ISSN
0002-9297
Published
1988-08-00
Pages
188-96
Language
English
Region
United States
NLM ID
0370475
PMCID
PMC1715345
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]