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PMID: 3446011 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Mapping of the gene coding for the human liver/bone/kidney isozyme of alkaline phosphatase to chromosome 1.

Annals of human genetics ·Vol. 50 ·No. 3 ·1986-00-00 ·Pages 229-35

Swallow DM, Povey S, Parkar M, Andrews PW, Harris H, Pym B, Goodfellow P

Abstract

The gene coding for the liver/bone/kidney isozyme of alkaline phosphatase, ALPL, has been mapped to human chromosome 1 using a monoclonal antibody TRA-2-54/2J and electrophoretic analysis to distinguish between the human and rodent isozymes in human/rodent somatic cell hybrids.

MeSH Terms

Alkaline Phosphatase/analysis,genetics Animals Cell Line Chromosome Mapping Chromosomes, Human, Pair 1 Genes Humans Hybrid Cells Isoenzymes/analysis,genetics Mice Radioimmunoassay Rats

Chemicals

Isoenzymes Alkaline Phosphatase

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Swallow D M

MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London.

Povey S

Parkar M

Andrews P W

Harris H

Pym B

Goodfellow P

Article Info

Journal

Annals of human genetics

Abbr.

Ann Hum Genet

ISSN

0003-4800

DOI

10.1111/j.1469-1809.1986.tb01043.x

Published

1986-00-00

Pages

229-35

Language

English

Region

England

NLM ID

0416661

Subset

Grants

NCI NIH HHS · CA29894 · United States

NIGMS NIH HHS · GM 27018 · United States

External Links

PubMed source DOI: 10.1111/j.1469-1809.1986.tb01043.x View journal details

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Mapping of the gene coding for the human liver/bone/kidney isozyme of alkaline phosphatase to chromosome 1.

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