Efficacy and safety of pefloxacin in the treatment of severe infections in patients hospitalized in intensive care units.

The Journal of antimicrobial chemotherapy ·Vol. 17 Suppl B ·1986-04-00 ·Pages 111-5

Lauwers S, Vincken W, Naessens A, Pierard D

Abstract

Sixteen patients, 14 with an infection of the lower respiratory tract and two with cholangitis, were treated with pefloxacin 400 mg bid or tid. The original pathogens were eradicated in all but one patient. Pefloxacin therapy resulted in clinical cure in 11 patients, three patients were improved clinically and in two patients a clinical failure was observed. No adverse effects were noticed during or after pefloxacin administration.

MeSH Terms

Adolescent Adult Aged Anti-Bacterial Agents/therapeutic use Bacteria/drug effects Bacterial Infections/complications,drug therapy,microbiology Bronchopneumonia/complications,drug therapy,microbiology Cholangitis/complications,drug therapy,microbiology Drug Evaluation Female Humans Intensive Care Units Male Middle Aged Norfloxacin/analogs & derivatives,therapeutic use Pefloxacin Pneumonia/complications,drug therapy,microbiology

Chemicals

Anti-Bacterial Agents Pefloxacin Norfloxacin

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Lauwers S

Vincken W

Naessens A

Pierard D

Article Info

Journal

The Journal of antimicrobial chemotherapy

Abbr.

J Antimicrob Chemother

ISSN

0305-7453

DOI

10.1093/jac/17.suppl_b.111

Published

1986-04-00

Pages

111-5

Language

English

Region

England

NLM ID

7513617

Subset

External Links

PubMed source DOI: 10.1093/jac/17.suppl_b.111 View journal details

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Efficacy and safety of pefloxacin in the treatment of severe infections in patients hospitalized in intensive care units.

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