Outbreak of infantile enteritis caused by enterotoxigenic Escherichia coli O6.H16.

Journal of clinical pathology ·Vol. 31 ·No. 3 ·1978-03-00 ·Pages 217-9

Rowe B, Gross RJ, Scotland SM, Wright AE, Shillom GN, Hunter NJ

Abstract

Ten out of 18 babies at risk developed enteritis in an outbreak in a special-care baby unit. Salmonella, Shigella, and Escherichia coli belonging to the traditional infantile enteropathogenic serogroups were not found in faeces from the babies and the staff, and no virus particles were found by electron microscopy. Detailed serotyping of E. coli showed that five of the 10 babies with diarrhoea and one of the eight without diarrhoea were excreting E. coli O6.H16. All six isolates of this serotype produced both heat-labile and heat-stable enterotoxin. Enterotoxigenic strains of E. coli O6.H16 have caused outbreaks of enteritis in adults in the USA and Japan.

MeSH Terms

Disease Outbreaks/epidemiology England Enteritis/epidemiology,etiology,microbiology Enterotoxins/biosynthesis Escherichia coli/isolation & purification,metabolism Escherichia coli Infections/epidemiology Feces/microbiology Hospitals, Maternity Humans Infant Infant, Newborn Nurseries, Hospital Serotyping

Chemicals

Enterotoxins

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Rowe B

Gross R J

Scotland S M

Wright A E

Shillom G N

Hunter N J

References (10)

10 references, click to expand

Enterotoxigenic Escherichia coli causing infantile enteritis in Britain.
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Outbreaks of acute enteritis due to heat-stable enterotoxin-producing strains of Escherichia coli.
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A NEW Escherichia coli O-group, O159, associated with outbreaks of enteritis in infants.
Scand J Infect Dis. 1976;8(3):195-8 PMID: 788145
Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli.
Infect Immun. 1974 Aug;10(2):320-7 PMID: 4368545
Enterotoxin testing of Escherichia coli causing epidemic infantile enteritis in the U.K.
Lancet. 1976 Mar 20;1(7960):629-31 PMID: 55904
Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture.
Science. 1974 Jan 25;183(4122):334-6 PMID: 4587905
Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu.
J Infect Dis. 1972 Apr;125(4):407-11 PMID: 4553083
Infantile diarrhea produced by heat-stable enterotoxigenic Escherichia coli.
N Engl J Med. 1976 Oct 14;295(16):849-53 PMID: 785259
Human diarrheal disease caused by enterotoxigenic Escherichia coli.
Annu Rev Microbiol. 1975;29:333-53 PMID: 1101807
Special Escherichia coli serotypes among enterotoxigenic strains from diarrhoea in adults and children.
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Article Info

Journal

Journal of clinical pathology

Abbr.

J Clin Pathol

ISSN

0021-9746

DOI

10.1136/jcp.31.3.217

Published

1978-03-00

Pages

217-9

Language

English

Region

England

NLM ID

0376601

PMCID

PMC1145231

Subset

External Links

PubMed source DOI: 10.1136/jcp.31.3.217 PMC Full Text View journal details

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Outbreak of infantile enteritis caused by enterotoxigenic Escherichia coli O6.H16.

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