Two-photon fluorogenic probe for visualizing PGP-1 activity in inflammatory tissues and serum from patients.

Chemical communications (Cambridge, England) ·Vol. 57 ·No. 97 ·2021-12-07

Bai H, Fang B, Wang X, Qin W, Chen Y, Zhang D, Li Y, Peng B, Yang X, Fu L, Li L

Abstract

A PGP-1-specific one/two-photon fluorogenic probe (BH1), capable of high sensitivity, super selectivity, and visual imaging of endogenous PGP-1 activity from live mammalian cells and serum/skin tissues from patients by using one/two-photon fluorescence microscopy (O/TPFM).

MeSH 主题词

Animals Cell Line Fluorescent Dyes/chemistry Humans Inflammation/enzymology,pathology Mice Microscopy, Fluorescence Photons Pyroglutamyl-Peptidase I/blood,metabolism

Article Info

Journal

Chemical communications (Cambridge, England)

Abbr.

Chem Commun (Camb)

ISSN

1364-548X

DOI

10.1039/d1cc05290j

Corresponding email

[email protected]
[email protected]
[email protected]

Published

2021-12-07

Language

English

Country/Region

England

NLM ID

9610838

External Links

PubMed source DOI: 10.1039/d1cc05290j View journal details

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Two-photon fluorogenic probe for visualizing PGP-1 activity in inflammatory tissues and serum from patients.

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