Autoimmunity in chronic lymphocytic leukaemia.

Journal of clinical pathology ·Vol. 39 ·No. 7 ·1986-07-00 ·Pages 713-6

Hamblin TJ, Oscier DG, Young BJ

Abstract

The prevalence of autoantibodies in B cell chronic lymphocytic leukaemia (B-CLL) was investigated. A lower prevalence of autoimmune haemolytic anaemia than that found in other series was found: large numbers of non-progressive stage A disease cases were included, in which the prevalence of autoimmune haemolytic anaemia is low. Non-haematological autoantibodies were no commoner than in age matched controls. Whatever explanation is offered for autoimmune phenomena in B-CLL it must take account of the fact that those phenomena are virtually confined to autoantibodies against the formed elements of the blood.

MeSH Terms

Aged Anemia, Hemolytic, Autoimmune/complications Autoantibodies/analysis B-Lymphocytes/immunology Coombs Test Female Humans Leukemia, Lymphoid/complications,immunology Male Thrombocytopenia/complications

Chemicals

Autoantibodies

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Hamblin T J

Oscier D G

Young B J

References (11)

11 references, click to expand

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Article Info

Journal

Journal of clinical pathology

Abbr.

J Clin Pathol

ISSN

0021-9746

DOI

10.1136/jcp.39.7.713

Published

1986-07-00

Pages

713-6

Language

English

Region

England

NLM ID

0376601

PMCID

PMC500029

Subset

External Links

PubMed source DOI: 10.1136/jcp.39.7.713 PMC Full Text View journal details

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