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PMID: 3490974 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Beta-lactamase production in the upper respiratory tract flora.

European journal of clinical microbiology ·Vol. 5 ·No. 5 ·1986-10-00 ·Pages 507-12

Eliasson I, Kamme C, Prellner K

Abstract

In order to determine the recovery rate of species of the genera Haemophilus and Moraxella (including subgenus Branhamella) from the upper respiratory tract and the incidence of beta-lactamase production within these genera, cultures were made of nose and throat swab specimens and adenoid tissue in 50 children undergoing adenoidectomy. Haemophilus influenzae was isolated from 92% of the children. All children harboured strains of Haemophilus spp. and in 46%, at least one strain produced the TEM-1 beta-lactamase. Branhamella catarrhalis and/or Moraxella nonliquefaciens were isolated from 82% of the children and strains producing the BRO-1 beta-lactamase from 34%. Overall, TEM-1 and/or BRO-1 producing strains were recovered from 60% of the investigated patients. The beta-lactamase production was found to be transferable by conjugation within the respective genera. It is suggested that the apathogenic species may be a source of transferable determinants mediating beta-lactamase production in the upper respiratory tract.

MeSH Terms
Adolescent Bacterial Infections/epidemiology Child Child, Preschool Female Haemophilus/enzymology,isolation & purification Haemophilus Infections/epidemiology Humans Infant Male Moraxella/enzymology,isolation & purification Nasal Cavity/microbiology Nasopharynx/microbiology Pharynx/microbiology beta-Lactamases/biosynthesis
Chemicals
beta-Lactamases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Eliasson I
Kamme C
Prellner K
References (29)
29 references, click to expand
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Article Info
Journal
European journal of clinical microbiology
Abbr.
Eur J Clin Microbiol
ISSN
0722-2211
DOI
10.1007/BF02017692
Published
1986-10-00
Pages
507-12
Language
English
Region
Germany
NLM ID
8219582
Subset
IM
External Links
PubMed source DOI: 10.1007/BF02017692
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