Abstract
By serological methods, all 83 known types of Streptococcus pneumoniae could be shown to possess C polysaccharide and F antigen. Cross-reactions due to these two antigens between pneumococci and a broad range of most other commonly encountered streptococci were examined. The presence of an antigen closely similar or identical to pneumococcal C polysaccharide was demonstrated in some strains of Streptococcus mitior. Therefore, we conclude that pneumococci cannot be identified serologically from mixed samples without culture. Streptococcal group C antiserum was found to cross-react with pneumococcal F antigen.
MeSH Terms
Antigens, Bacterial/immunology
Antigens, Heterophile/immunology
Cross Reactions
Forssman Antigen/immunology
Immunoelectrophoresis
Immunoelectrophoresis, Two-Dimensional
Polysaccharides, Bacterial/immunology
Streptococcus/immunology
Streptococcus pneumoniae/immunology
Chemicals
Antigens, Bacterial
Antigens, Heterophile
Polysaccharides, Bacterial
polysaccharide C-substance (Streptococcus)
Forssman Antigen
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Sørensen U B
World Health Organization Collaborating Centre for Reference and Research on Pneumococci, Statens Seruminstitut, Copenhagen S, Denmark.
Henrichsen J
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