Pairing properties of the methylester of 5-carboxymethyl uridine in the wobble position of yeast tRNA3Arg.

Biochimica et biophysica acta ·Vol. 518 ·No. 3 ·1978-05-23 ·Pages 530-4

Weissenbach J, Dirheimer G

Abstract

At optimum magnesium concentration (10 mM) both yeast tRNA1Arg and tRNA3Arg are able to bind to poly (A,G) and A-G-A in presence of Escherichia coli robisomes. With A-G-G only tRNA1Arg ginds, wherea tRNA3Arg (anticodon mcm5 U-C-U) is not bound. This result means that the methylcarboxymethyl substituant in position 5 of U prevents its wobble with G.

MeSH Terms

Anticodon/metabolism Arginine/metabolism Base Sequence Binding Sites Codon/metabolism Polyribonucleotides/metabolism Protein Biosynthesis RNA, Messenger/metabolism RNA, Transfer/metabolism Ribosomes/metabolism Saccharomyces cerevisiae/metabolism Uridine/analogs & derivatives,metabolism

Chemicals

Anticodon Codon Polyribonucleotides RNA, Messenger RNA, Transfer Arginine Uridine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Weissenbach J

Dirheimer G

Article Info

Journal

Biochimica et biophysica acta

Abbr.

Biochim Biophys Acta

ISSN

0006-3002

DOI

10.1016/0005-2787(78)90171-5

Published

1978-05-23

Pages

530-4

Language

English

Region

Netherlands

NLM ID

0217513

Subset

External Links

PubMed source DOI: 10.1016/0005-2787(78)90171-5

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Pairing properties of the methylester of 5-carboxymethyl uridine in the wobble position of yeast tRNA3Arg.

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