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PMID: 3516675 Published · ppublish English Journal Article

Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals.

Environmental mutagenesis ·Vol. 8 Suppl 7 ·1986-00-00 ·Pages 1-119

Mortelmans K, Haworth S, Lawlor T, Speck W, Tainer B, Zeiger E

Abstract

This publication includes data of Salmonella mutagenicity results on 270 coded chemicals, encompassing 329 tests performed by three laboratories under contract to the National Toxicology Program (NTP). The preincubation modification of the Salmonella/mammalian microsome assay was used to test chemicals in up to five Salmonella strains in the presence and absence of rat and hamster liver S-9. With a few exceptions, inter- and intralaboratory reproducibility was good.

MeSH Terms
Animals Biotransformation Cricetinae Microsomes, Liver/metabolism Mutagenicity Tests/methods,standards Mutagens Rats Salmonella typhimurium/drug effects,genetics
Chemicals
Mutagens
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Mortelmans K
Haworth S
Lawlor T
Speck W
Tainer B
Zeiger E
Article Info
Journal
Environmental mutagenesis
Abbr.
Environ Mutagen
ISSN
0192-2521
Published
1986-00-00
Pages
1-119
Language
English
Region
United States
NLM ID
7909737
Subset
IM
External Links
PubMed source
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