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PMID: 3516881 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Homologous regions within M protein genes in group A streptococci of different serotypes.

Infection and immunity ·Vol. 52 ·No. 2 ·1986-05-00 ·Pages 609-12

Scott JR, Hollingshead SK, Fischetti VA

Abstract

DNA hybridization with probes from the structural gene for the M6 protein shows that the carboxy-terminal region (proximal to the cell surface) is conserved among strains of different M serotypes. The amino-terminal region, which is more available to immunological surveillance, exhibits greater variation.

MeSH Terms
Antigens, Bacterial/genetics Bacterial Proteins/genetics DNA, Bacterial/genetics Genes Genes, Bacterial Streptococcus pyogenes/genetics
Chemicals
Antigens, Bacterial Bacterial Proteins DNA, Bacterial
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Scott J R
Hollingshead S K
Fischetti V A
References (19)
19 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.52.2.609-612.1986
Published
1986-05-00
Pages
609-12
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC261044
Subset
IM
Grants
NIAID NIH HHS · AI20723 · United States
External Links
PubMed source DOI: 10.1128/iai.52.2.609-612.1986 PMC Full Text View journal details
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