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PMID: 351803 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Attraction by repellents: an error in sensory information processing by bacterial mutants.

Science (New York, N.Y.) ·Vol. 201 ·No. 4350 ·1978-07-07 ·Pages 63-5

Muskavitch MA, Kort EN, Springer MS, Goy MF, Adler J

Abstract

Normal Escherichia coli bacteria are repelled by acetate, benzoate, and indole and attracted by alpha-aminoisobutyrate. We have isolated mutants that are attracted to acetate, benzoate, and indole and may be repelled by alpha-aminoisobutyrate. These reversed-taxis mutants are defective in a central processing component: a set of methylated proteins known as MCP 1. The mechanism of reversal of taxis is discussed.

MeSH Terms
Acetates Bacterial Proteins/genetics,physiology Benzoates Chemotaxis Escherichia coli/genetics,physiology Indoles Methylation Mutation Receptors, Drug/physiology
Chemicals
Acetates Bacterial Proteins Benzoates Indoles Receptors, Drug
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Muskavitch M A
Kort E N
Springer M S
Goy M F
Adler J
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1978-07-07
Pages
63-5
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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