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PMID: 3551837 Published · ppublish English Clinical Trial Comparative Study Journal Article Randomized Controlled Trial

Single-dose ciprofloxacin at 100 versus 250 mg for treatment of uncomplicated urinary tract infections in women.

Antimicrobial agents and chemotherapy ·Vol. 31 ·No. 2 ·1987-02-00 ·Pages 354-6

Garlando F, Rietiker S, Täuber MG, Flepp M, Meier B, Lüthy R

Abstract

Two single-dose regimens of ciprofloxacin, 100 and 250 mg, were compared in the treatment of uncomplicated urinary tract infections in women. Cure rates 5 days after therapy did not significantly differ, being 16 of 19 (84%) with the 100-mg dose and 17 of 19 (89%) with the 250-mg dose. Ciprofloxacin was well tolerated.

MeSH Terms
Adolescent Adult Ciprofloxacin/administration & dosage,pharmacology,therapeutic use Drug Administration Schedule Escherichia coli/drug effects Escherichia coli Infections/drug therapy Female Humans Middle Aged Recurrence Staphylococcal Infections/drug therapy Staphylococcus/drug effects Urinary Tract Infections/drug therapy
Chemicals
Ciprofloxacin
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Garlando F
Rietiker S
Täuber M G
Flepp M
Meier B
Lüthy R
References (16)
16 references, click to expand
  1. Single-dose treatment of acute urinary tract infection: a controlled trial.
    Br Med J. 1967 Sep 9;3(5566):649-51 PMID: 6038338
  2. Treatment of lower urinary tract infections with single-dose trimethoprim-sulfamethoxazole.
    J Fam Pract. 1985 Jun;20(6):551-7 PMID: 3873511
  3. Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic.
    N Engl J Med. 1978 Feb 23;298(8):413-6 PMID: 340949
  4. Treatment of urinary tract infection with a single dose of trimethoprim-sulfamethoxazole.
    Can Med Assoc J. 1978 Mar 4;118(5):551-2 PMID: 630515
  5. Single-dose treatment of cystitis.
    JAMA. 1980 Aug 8;244(6):591-2 PMID: 7392158
  6. Effective treatment of urinary tract infections.
    Infection. 1980;Suppl 1:70-4 PMID: 6772580
  7. [Single-dose gentamicin treatment and simultaneous localization of urinary-tract infections (author's transl)].
    Dtsch Med Wochenschr. 1981 Oct 23;106(43):1420-3 PMID: 7285825
  8. Single-dose cefaclor therapy of urinary tract infection. Evaluation of antibody-coated bacteria test and C-reactive protein assay as predictors of cure.
    Am J Med. 1981 Nov;71(5):841-5 PMID: 7304657
  9. Acute dysuria in women.
    N Engl J Med. 1984 Feb 9;310(6):368-75 PMID: 6361571
  10. Multiple-dose pharmacokinetics and safety of ciprofloxacin in normal volunteers.
    Antimicrob Agents Chemother. 1984 Nov;26(5):741-4 PMID: 6517556
  11. Management of recurrent urinary tract infections with patient-administered single-dose therapy.
    Ann Intern Med. 1985 Mar;102(3):302-7 PMID: 3871597
  12. [Single-dose versus 5-day cotrimoxazole therapy in acute symptomatic urinary tract infections in the female. A prospective randomized study].
    Geburtshilfe Frauenheilkd. 1984 Dec;44(12):803-7 PMID: 6396153
  13. A randomised comparison of single-dose vs. three-day and ten-day therapy with trimethoprim-sulfamethoxazole for acute cystitis in women.
    Scand J Infect Dis. 1984;16(4):373-9 PMID: 6396834
  14. Treatment of bacterial cystitis with a single dose of trimethoprim, co-trimoxazole or amoxycillin compared with a course of trimethoprim.
    N Z Med J. 1985 May 22;98(779):387-9 PMID: 3887254
  15. Effect of standard breakfast on drug absorption and multiple-dose pharmacokinetics of ciprofloxacin.
    Antimicrob Agents Chemother. 1985 Mar;27(3):350-2 PMID: 3158273
  16. The treatment of urinary infection by means of a single dose of cephaloridine.
    Postgrad Med J. 1970 Oct;:Suppl:65-9 PMID: 4922710
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
Published
1987-02-00
Pages
354-6
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC174727
Subset
IM
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