DNA sequence of the mini-insertion IS2--6 and its relation to the sequence of IS2.

Nature ·Vol. 275 ·No. 5681 ·1978-10-19 ·Pages 611-7

Ghosal D, Saedler H

Abstract

In polar IS2 abolishes galactose operon expression. Operon activity is restored by a 108 base pair mini-insertion within IS2 called IS2--6. The DNA sequences of the gal operon-IS2 junction, the parental IS2 region undergoing sequence rearrangements and IS2--6 itself are reported. IS2--6 is composed of sequence intervals present in both strands of IS2.

MeSH Terms

Base Sequence Chromosome Mapping Chromosomes, Bacterial DNA Replication DNA, Bacterial/genetics Escherichia coli/genetics,ultrastructure Galactose/genetics Operon

Chemicals

DNA, Bacterial Galactose

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Ghosal D

Saedler H

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/275611a0

Published

1978-10-19

Pages

611-7

Language

English

Region

England

NLM ID

0410462

Subset

Databases

GENBANK

M10675

External Links

PubMed source DOI: 10.1038/275611a0 View journal details

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DNA sequence of the mini-insertion IS2--6 and its relation to the sequence of IS2.

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