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PMID: 361710 Published · ppublish English Journal Article

Stimulation of deletions in the Escherichia coli chromosome by partially induced Mucts62 prophages.

Journal of bacteriology ·Vol. 136 ·No. 2 ·1978-11-00 ·Pages 477-83

Faelen M, Toussaint A

Abstract

Deletion of bacterial DNA fragments is stimulated in induced Mucts62 lysogens. The host genes located proximally to the prophage are more frequently lost than those which are unlinked to the Mu genome. Genes located on either side of a Mu genome are deleted in the same manner. Like the other Mu-induced rearrangements, this process is recA independent and requires the participation of Mu DNA, as indicated by the fact that a phage genome always replaces the deleted genes. Data are presented which strongly suggest that both ends of the Mu genome are involved in deletion formation.

MeSH Terms
Chromosomes, Bacterial Coliphages/genetics DNA, Bacterial/genetics DNA, Viral/genetics Escherichia coli/genetics Galactose/metabolism Genes Genes, Viral Lysogeny Operon Tryptophan/biosynthesis
Chemicals
DNA, Bacterial DNA, Viral Tryptophan Galactose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Faelen M
Toussaint A
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30 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.136.2.477-483.1978
Published
1978-11-00
Pages
477-83
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC218569
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.136.2.477-483.1978 PMC Full Text View journal details
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