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PMID: 3623705 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Absence of lipopolysaccharide in the Lyme disease spirochete, Borrelia burgdorferi.

Infection and immunity ·Vol. 55 ·No. 9 ·1987-09-00 ·Pages 2311-3

Takayama K, Rothenberg RJ, Barbour AG

Abstract

We were unable to demonstrate the presence of the classic enterobacterium-type lipopolysaccharide in the cells of the Lyme disease spirochete, Borrelia burgdorferi B31. This finding was primarily based on chemical analysis and the absence of free lipid A upon mild acid hydrolysis of the appropriate cell extracts. These results do not preclude the possible existence of an unusual lipopolysaccharide-like compound(s) in B. burgdorferi.

MeSH Terms
Borrelia/analysis Borrelia burgdorferi Lipid A/analysis Lipopolysaccharides/analysis Lyme Disease/microbiology Polysaccharides, Bacterial/analysis
Chemicals
Lipid A Lipopolysaccharides Polysaccharides, Bacterial
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Takayama K
Rothenberg R J
Barbour A G
References (18)
18 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.55.9.2311-2313.1987
Published
1987-09-00
Pages
2311-3
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC260699
Subset
IM
Grants
NIAID NIH HHS · AI-24424 · United States
NIGMS NIH HHS · GM-36054 · United States
External Links
PubMed source DOI: 10.1128/iai.55.9.2311-2313.1987 PMC Full Text View journal details
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