Sequence homologies of (guanosine + cytidine)-rich regions of mitochondrial DNA of Saccharomyces cerevisiae.

The nucleotide sequences of two distinct regions of mitochrondrial DNA of Saccharomyces cerevisiae are reported. The regions studied have a high content of G + C (45%) and contain closely spaced Hpa II and Hae III restriction sites. Both regions have sequences that are homologous over a lenght of 47 base-pairs. In addition, the two regions are highly palindromic. These data support certain aspects of the organization of mitochondrial DNA proposed by Prunell and Bernardi (Prunell, A., and Bernardi, G. (1977) J. Mol. Biol. 110, 53--74).