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PMID: 364320 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Synthesis of growth hormone by bacteria.

Nature ·Vol. 276 ·No. 5690 ·1978-00-00 ·Pages 795-8

Seeburg PH, Shine J, Martial JA, Ivarie RD, Morris JA, Ullrich A, Baxter JD, Goodman HM

Abstract

A hybrid gene was constructed between the beta-lactamase gene of plasmid pBR322 and the cloned coding sequence for rat growth hormone. This gene is expressed in bacteria and growth hormone sequences are detectable by immunological methods.

MeSH Terms
Animals DNA, Recombinant Escherichia coli/genetics Genes Genetic Linkage Growth Hormone/genetics,immunology Methods Plasmids Radioimmunoassay Rats beta-Lactamases/genetics
Chemicals
DNA, Recombinant Growth Hormone beta-Lactamases
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Seeburg P H
Shine J
Martial J A
Ivarie R D
Morris J A
Ullrich A
Baxter J D
Goodman H M
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/276795a0
Published
1978-00-00
Pages
795-8
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/276795a0 View journal details
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