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PMID: 36548762 Published · epublish English Journal Article Research Support, Non-U.S. Gov't

Body Composition of Healthy Cats and Cats with Chronic Kidney Disease Fed on a Dry Diet Low in Phosphorus with Maintenance Protein.

Toxins ·Vol. 14 ·No. 12 ·2022-00-09

Machado DP, Ruberti B, Teixeira FA, Vendramini THA, Pfrimer K, Chacar FC, Balieiro JCC, Pontieri CFF, Brunetto MA

Abstract

The aim was to evaluate the effect of feeding a low-phosphorus and maintenance protein diet in healthy cats and cats with chronic kidney disease (CKD) with IRIS stages 1 (CKD-1) and 2 (CKD-2). Cats were initially fed a senior diet (30 days) followed by the renal diet (60 days). Body composition, body weight (BW), muscle mass score (MMS), and body condition score (BCS) were assessed before (T30) and after renal diet intake (T60). General mixed linear models were used to assess the effects of fixed groups and moments (T30 × T60), as well as their interaction, in addition to the random effects of animals within each group. Unlike healthy cats and cats with CKD-1, cats with CKD-2 had a loss of BW, lower BCS (p < 0.005), and lower MMS (p = 0.0008) after 60 days of consuming the renal diet. The fat mass and lean body mass (LBM), determined by the deuterium isotopes method, did not change in all cats between T0 and T60. In healthy cats and cats with CKD-1, the renal diet resulted in maintenance of BW, BCS and MMS; but cats with CKD-2 presented lower BCS and did not reduce phosphatemia after consumption.

Keywords
azotemia body condition score feline lean mass
MeSH 主题词
Cats Animals Phosphorus Diet/veterinary Body Weight Renal Insufficiency, Chronic/veterinary Body Composition
化学物质
Phosphorus
作者与单位
共 9 位作者,点击展开单位 / ORCID
Machado Daniela P
School of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo (USP), 225, Duque de Caxias Norte Ave, Pirassununga, São Paulo 13635-900, Brazil. | Nutritional Development Center, Grandfood Industria e Comercio LTDA (PremieRpet®), Luiz Augusto de Oliveira Hwy, km 204, Dourado, São Paulo 13590-000, Brazil.
Ruberti Bruna
School of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo (USP), 225, Duque de Caxias Norte Ave, Pirassununga, São Paulo 13635-900, Brazil.
Teixeira Fabio A
School of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo (USP), 225, Duque de Caxias Norte Ave, Pirassununga, São Paulo 13635-900, Brazil.
Vendramini Thiago H A
School of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo (USP), 225, Duque de Caxias Norte Ave, Pirassununga, São Paulo 13635-900, Brazil.
Pfrimer Karina
Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo 14049-900, Brazil.
Chacar Fernanda C
School of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo (USP), 225, Duque de Caxias Norte Ave, Pirassununga, São Paulo 13635-900, Brazil.
Balieiro Julio C C
School of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo (USP), 225, Duque de Caxias Norte Ave, Pirassununga, São Paulo 13635-900, Brazil.
Pontieri Cristiana F F
Nutritional Development Center, Grandfood Industria e Comercio LTDA (PremieRpet®), Luiz Augusto de Oliveira Hwy, km 204, Dourado, São Paulo 13590-000, Brazil.
Brunetto Marcio A
School of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo (USP), 225, Duque de Caxias Norte Ave, Pirassununga, São Paulo 13635-900, Brazil.
Article Info
Journal
Toxins
Abbr.
Toxins (Basel)
ISSN
2072-6651
Published
2022-00-09
电子出版
2022-00-09
Language
English
Country/Region
Switzerland
NLM ID
101530765
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