The derivation and interpretation of control coefficients.

The Biochemical journal ·Vol. 247 ·No. 1 ·1987-10-01 ·Pages 113-20

Crabtree B, Newsholme EA

Abstract

1. Equations for control coefficients are derived by using a method that generates all the control coefficients for a system in a single procedure. This requires solving fewer simultaneous equations than an equivalent method based on 'control theorems'. 2. The interpretation of control coefficients is discussed: in particular, it is shown that these functions are unsatisfactory as measures of 'control' and are perhaps best used as a means of testing control theories (models).

MeSH Terms

Mathematics Metabolism Models, Biological

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Crabtree B

Rowett Research Institute, Bucksburn, Aberdeen, Scotland, U.K.

Newsholme E A

References (15)

15 references, click to expand

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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj2470113

Published

1987-10-01

Pages

113-20

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1148377

Subset

External Links

PubMed source DOI: 10.1042/bj2470113 PMC Full Text View journal details

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The derivation and interpretation of control coefficients.

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