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PMID: 37153332 Published · epublish English Journal Article

Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City.

Lopez-Garibay LA, Guevara-Valmaña O, Telich-Tarriba JE, Navarro-Barquín DF, Haro-Alvarez N, Andrade-Delgado L, Martínez-Wagner R

Abstract

Background  Craniofacial fibrous dysplasia (CFD) is an uncommon benign condition in which a bone is replaced by fibrous tissue. An adequate clinical characterization considering the number of affected bones and functional impairment is important to determine the most effective surgical intervention for its management. This study aims to present our institution's experience in the evaluation and management of CFD. Methods  This was a retrospective study that included patients with CFD managed at our institution. Data included demographic characteristics, afflicted bones, surgical procedures performed, and recurrence. Results are presented as mean and percentages. Recurrence-free years and association between the type of surgery and recurrence was evaluated. Results  Eighteen patients were included (11 females, 61%). The zygomatic, maxillary, and frontal bones were the most commonly affected with eight (18%) cases each. The most common procedure was bone burring, with 36 procedures. Recurrence was more prevalent after burring (58.3%) and occurred earlier than in the bone resection group (13 vs. 15 years, p > 0.05). Conclusion  Surgery continues to be the cornerstone of CFD treatment. Bone burring is effective for debulking and contouring but increases the risk for recurrence. An individualized approach should be tailored according to the anatomical location of the disease, type of CFD, behavior of the lesion, and accompanying clinical complaints.

Keywords
GTP-binding proteins craniofacial fibrous dysplasia fibrous dysplasia follow-up studies mandibular osteotomy polyostotic recurrence
作者与单位
共 7 位作者,点击展开单位 / ORCID
Lopez-Garibay Luis Alejandro
Plastic and Reconstructive Surgery Division, Hospital General "Dr Manuel Gea Gonzalez" Postgraduate Division of the Medical School, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.
Guevara-Valmaña Osvaldo
Plastic and Reconstructive Surgery Division, Hospital General "Dr Manuel Gea Gonzalez" Postgraduate Division of the Medical School, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.
Telich-Tarriba Jose Eduardo ORCID
Plastic and Reconstructive Surgery Division, Hospital General "Dr Manuel Gea Gonzalez" Postgraduate Division of the Medical School, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.
Navarro-Barquín David Felipe
Plastic and Reconstructive Surgery Division, Hospital General "Dr Manuel Gea Gonzalez" Postgraduate Division of the Medical School, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.
Haro-Alvarez Natalia
Plastic and Reconstructive Surgery Division, Hospital General "Dr Manuel Gea Gonzalez" Postgraduate Division of the Medical School, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.
Andrade-Delgado Laura ORCID
Plastic and Reconstructive Surgery Division, Hospital General "Dr Manuel Gea Gonzalez" Postgraduate Division of the Medical School, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.
Martínez-Wagner Rogelio
Plastic and Reconstructive Surgery Division, Hospital General "Dr Manuel Gea Gonzalez" Postgraduate Division of the Medical School, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.
Article Info
Journal
Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India
Abbr.
Indian J Plast Surg
ISSN
0970-0358
Published
2023-04-00
电子出版
2023-00-13
页码
124-129
Language
English
Country/Region
Germany
NLM ID
8405356
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