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PMID: 37158263 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Correlation of Nasal Mucosal Temperature and Nasal Patency-A Computational Fluid Dynamics Study.

The Laryngoscope ·Vol. 133 ·No. 6 ·2023-00-00 ·Pages 1328-1335

Tjahjono R, Salati H, Inthavong K, Singh N

Abstract

Recent evidence suggests that detection of nasal mucosal temperature, rather than direct airflow detection, is the primary determinant of subjective nasal patency. This study examines the role of nasal mucosal temperature in the perception of nasal patency using in vivo and computational fluid dynamics (CFD) measurements. Healthy adult participants completed Nasal Obstruction Symptom Evaluation (NOSE) and Visual Analogue Scale (VAS) questionnaires. A temperature probe measured nasal mucosal temperature at the vestibule, inferior turbinate, middle turbinate, and nasopharynx bilaterally. Participants underwent a CT scan, used to create a 3D nasal anatomy model to perform CFD analysis of nasal mucosal and inspired air temperature and heat flux along with mucosal surface area where heat flux >50 W/m2 (SAHF50). Eleven participants with a median age of 27 (IQR 24; 48) were recruited. Probe-measured temperature values correlated strongly with CFD-derived values (r = 0.87, p < 0.05). Correlations were seen anteriorly in the vestibule and inferior turbinate regions between nasal mucosal temperature and unilateral VAS (r = 0.42-0.46; p < 0.05), between SAHF50 and unilateral VAS (r = -0.31 to -0.36; p < 0.05) and between nasal mucosal temperature and SAHF50 (r = -0.37 to -0.41; p < 0.05). Subjects with high patency (VAS ≤10) had increased heat flux anteriorly compared with lower patency subjects (VAS >10; p < 0.05). Lower nasal mucosal temperature and higher heat flux within the anterior nasal cavity correlates with a perception of improved unilateral nasal patency in healthy individuals. 4 Laryngoscope, 133:1328-1335, 2023.

Keywords
computational fluid dynamics heat flux nasal airflow nasal mucosal temperature nasal patency
MeSH Terms
Adult Humans Temperature Hydrodynamics Computer Simulation Nasal Cavity/diagnostic imaging Nasal Obstruction/diagnostic imaging Nasal Mucosa
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Tjahjono Richard ORCID
Department of Otolaryngology Head and Neck Surgery, Westmead Hospital, Sydney, New South Wales, Australia. | Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Salati Hana
Faculty of Engineering, RMIT University, Melbourne, Victoria, Australia.
Inthavong Kiao ORCID
Faculty of Engineering, RMIT University, Melbourne, Victoria, Australia.
Singh Narinder
Department of Otolaryngology Head and Neck Surgery, Westmead Hospital, Sydney, New South Wales, Australia. | Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
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Article Info
Journal
The Laryngoscope
Abbr.
Laryngoscope
ISSN
1531-4995
DOI
10.1002/lary.30327
Published
2023-00-00
Epub
2022-00-03
Pages
1328-1335
Language
English
Region
United States
NLM ID
8607378
Subset
IM
External Links
PubMed source DOI: 10.1002/lary.30327 View journal details
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