Home LiteratureArticle Details
PMID: 37292014 Published · ppublish English Journal Article

CFD analysis on blood flow inside a symmetric stenosed artery: Physiology of a coronary artery disease.

Science progress ·Vol. 106 ·No. 2 ·2023-00-00 ·页码 368504231180092

Akhtar S, Hussain Z, Nadeem S, Najjar IMR, Sadoun AM

Abstract

This research article interprets the computational fluid dynamics analysis on blood flow inside a symmetric stenosed artery. The current problem models the blood flow inside the left coronary artery as having a symmetric stenosis in the central region. A comprehensive physiological examination of coronary artery disease is numerically evaluated by using the computational fluid dynamics toolbox Open-Field Operation And Manipulation. There are no assumptions of mild stenosis taken into account since the considered stenosis has an exactly measured length, height and position, etc. The blood flow problem is modeled for the non-Newtonian Casson fluid with unsteady, laminar, and incompressible flow assumptions. The underlying problem is solved numerically in its dimensional form. A thorough graphical analysis is provided on the blood flow simulations, pressure profile, velocity line graphs, pressure line graphs, and streamlines for the left coronary artery having a symmetric stenosis formation. The considered artery is divided into three sections, i.e. pre-stenosis, post-stenosis, and stenosis region, and the velocity and pressure line graphs are plotted for these considered regions. The graphical illustrations provide a detailed analysis of how the blood flow is affected inside the left coronary artery due to coronary artery disease. These pre- and post-stenosis velocity line graphs reveal two intriguing results: In the pre-stenosis zone, the velocity increases with increasing axial coordinate length, whereas in the post-stenosis region, the velocity decreases with rising axial coordinate length. It is evident that as the flow moves toward the stenosis region, the flow profile rises; yet, after passing through the stenosis zone, the flow profile begins to fall as the flow moves away from the stenosis region.

Keywords
Blood flow coronary artery disease non-Newtonian casson fluid symmetric stenosis
MeSH 主题词
Humans Constriction, Pathologic Coronary Artery Disease Coronary Stenosis Computer Simulation Models, Cardiovascular
作者与单位
共 5 位作者,点击展开单位 / ORCID
Akhtar Salman ORCID
Department of Mathematics, Quaid-i-Azam University, Islamabad, Pakistan.
Hussain Zahir
School of Engineering, University of Leicester, Leicester, UK.
Nadeem Sohail ORCID
Department of Mathematics, Quaid-i-Azam University, Islamabad, Pakistan. | Department of Mathematics, Wenzhou University, Wenzhou, China.
Najjar I M R
Mechanical Engineering Department, Faculty of Engineering, King Abdulaziz University, Jeddah, Saudi Arabia.
Sadoun A M
Mechanical Engineering Department, Faculty of Engineering, King Abdulaziz University, Jeddah, Saudi Arabia.
Article Info
Journal
Science progress
Abbr.
Sci Prog
ISSN
2047-7163
Published
2023-00-00
页码
368504231180092
Language
English
Country/Region
England
NLM ID
0411361
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]