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PMID: 3771756 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Evidence for production of an enterotoxin and cholera toxin cross-reactive factor by Aeromonas hydrophila.

Journal of clinical microbiology ·Vol. 24 ·No. 4 ·1986-10-00 ·Pages 661-4

Chopra AK, Houston CW, Genaux CT, Dixon JD, Kurosky A

Abstract

The enterotoxins produced by Aeromonas hydrophila were examined for biological activity by the rabbit ileal loop and suckling mouse assays, as well as by elongation of CHO cells. Antigenic evaluation of the culture filtrates from various isolates of A. hydrophila was performed by enzyme-linked immunosorbent assay with anti-cholera toxin and anti-Aeromonas enterotoxin. Heat stability data demonstrated the presence of a heat-labile cholera toxin cross-reactive factor and a heat stable non-cholera toxin cross-reactive enterotoxin. The biological activities of both enterotoxins were heat labile at 56 degrees C for 20 min.

MeSH Terms
Aeromonas/metabolism Animals Animals, Suckling Cells, Cultured Cholera Toxin/immunology Cross Reactions Cytotoxins/biosynthesis Enterotoxins/biosynthesis,immunology Enzyme-Linked Immunosorbent Assay Hemolysin Proteins/biosynthesis Humans Mice Rabbits
Chemicals
Cytotoxins Enterotoxins Hemolysin Proteins Cholera Toxin
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Chopra A K
Houston C W
Genaux C T
Dixon J D
Kurosky A
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20 references, click to expand
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Article Info
Journal
Journal of clinical microbiology
Abbr.
J Clin Microbiol
ISSN
0095-1137
DOI
10.1128/jcm.24.4.661-664.1986
Published
1986-10-00
Pages
661-4
Language
English
Region
United States
NLM ID
7505564
PMCID
PMC268996
Subset
IM
Grants
NIAID NIH HHS · I-R23-AI 21075-01 · United States
External Links
PubMed source DOI: 10.1128/jcm.24.4.661-664.1986 PMC Full Text View journal details
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