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PMID: 3794727 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Cerebral amyloid angiopathy in dementia and old age.

Journal of neurology, neurosurgery, and psychiatry ·Vol. 49 ·No. 11 ·1986-11-00 ·Pages 1221-6

Esiri MM, Wilcock GK

Abstract

A necropsy study of 159 elderly patients drawn mainly from a prospectively assessed geriatric hospital population was carried out to investigate the relationship of cerebral amyloid angiopathy to Alzheimer's disease, other CNS disease and ageing. About half the patients were demented and the majority of these had Alzheimer's disease. In Alzheimer's disease there was an incidence of cerebral amyloid angiopathy of 82%. Among the other groups of patients, both demented and non-demented, the incidence of cerebral amyloid angiopathy was a little over 30%, and remained constant between 60 and 102 years of age.

MeSH Terms
Aged Aged, 80 and over Alzheimer Disease/complications Amyloid/metabolism Amyloidosis/complications Blood Vessels/metabolism Brain/blood supply Cerebral Infarction/complications Cerebrovascular Disorders/complications Congo Red Female Histocytochemistry Humans Male Middle Aged
Chemicals
Amyloid Congo Red
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Esiri M M
Wilcock G K
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Article Info
Journal
Journal of neurology, neurosurgery, and psychiatry
Abbr.
J Neurol Neurosurg Psychiatry
ISSN
0022-3050
DOI
10.1136/jnnp.49.11.1221
Published
1986-11-00
Pages
1221-6
Language
English
Region
England
NLM ID
2985191R
PMCID
PMC1029068
Subset
IM
External Links
PubMed source DOI: 10.1136/jnnp.49.11.1221 PMC Full Text View journal details
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