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PMID: 3859751 Published · ppublish English Case Reports Journal Article

Systemic pseudallescheriasis in a patient with acute myelocytic leukemia.

Mycopathologia ·Vol. 90 ·No. 2 ·1985-05-00 ·Pages 85-9

Smith AG, Crain SM, Dejongh C, Thomas GM, Vigorito RD

Abstract

Presented is a case of widely disseminated systemic pseudallescheriasis in a 41 year old male with acute myelocytic leukemia. The immediate cause of death appeared to be due to an extensive invasion of the lungs which showed massive intra-alveolar hemorrhages, congestion, mycotic thrombi, and multiple fungal lesions in all lobes. Pseudallescheria boydii was diagnosed histopathologically by virtue of its characteristic conidia present in miliary lesions throughout a wide range of host's tissues, including the brain and the thyroid. Three antemortem blood specimens cultured during the patient's final hospital stay were positive for the fungus. It was concluded the fungemia was responsible for the rapid and widespread dispersion of P. boydii in this debilitated patient who was granulocytopenic and immunosuppressed.

MeSH Terms
Adult Ascomycota Humans Leukemia, Myeloid, Acute/complications,microbiology Lung/microbiology Male Mycoses/complications Skin/microbiology Thyroid Gland/microbiology
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Smith A G
Crain S M
Dejongh C
Thomas G M
Vigorito R D
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29 references, click to expand
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Article Info
Journal
Mycopathologia
Abbr.
Mycopathologia
ISSN
0301-486X
DOI
10.1007/BF00436855
Published
1985-05-00
Pages
85-9
Language
English
Region
Netherlands
NLM ID
7505689
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00436855 View journal details
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