Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules.

Animals Base Sequence Biological Evolution Blood Coagulation Factors/genetics Calcium/metabolism Endopeptidases/genetics Epidermal Growth Factor/genetics Factor IX/genetics Factor X/genetics Fibrinolytic Agents Fibronectins/genetics Glycoproteins/genetics Humans Peptides/genetics Plasminogen/genetics Plasminogen Activators/genetics Protein C Protein Conformation Protein Sorting Signals Prothrombin/genetics Serine Endopeptidases Structure-Activity Relationship Urokinase-Type Plasminogen Activator/genetics Vitamin K/pharmacology

Blood Coagulation Factors Fibrinolytic Agents Fibronectins Glycoproteins Peptides Protein C Protein Sorting Signals Vitamin K Epidermal Growth Factor Prothrombin Factor IX Factor X Plasminogen Endopeptidases Plasminogen Activators Serine Endopeptidases Urokinase-Type Plasminogen Activator Calcium