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PMID: 3902627 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Susceptibility and HLA-B27 in post-dysenteric arthropathies.

Immunology ·Vol. 56 ·No. 2 ·1985-10-00 ·Pages 377-9

van Bohemen CG, Lionarons RJ, van Bodegom P, Dinant HJ, Landheer JE, Nabbe AJ, Grumet FC, Zanen HC

Abstract

A recent outbreak of bacillary dysentery in The Netherlands revealed that, despite the close association of HLA-B27 with post-dysenteric or reactive arthritis (ReA), not even in one family did all HLA-B27 positive patients infected by an arthritogenic bacterium, develop ReA. This dissociation shows that additional factors beside B27 may determine susceptibility to ReA.

MeSH Terms

Adolescent Adult Antibodies, Bacterial/analysis Arthritis/etiology,immunology Disease Susceptibility Dysentery, Bacillary/complications Female HLA Antigens/analysis HLA-B27 Antigen Humans Male Middle Aged Prohibitins Shigella flexneri/immunology

Chemicals

Antibodies, Bacterial HLA Antigens HLA-B27 Antigen PHB2 protein, human Prohibitins

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

van Bohemen C G

Lionarons R J

van Bodegom P

Dinant H J

Landheer J E

Nabbe A J

Grumet F C

Zanen H C

References (3)

3 references, click to expand

Letter: HL-A 27 and ankylosing spondylitis.
Lancet. 1975 Mar 1;1(7905):520 PMID: 46985
Reiter's syndrome and reactive arthritis in perspective.
N Engl J Med. 1983 Dec 29;309(26):1606-15 PMID: 6358890
Monoclonal antibody (B27M2) subdividing HLA-B27.
Hum Immunol. 1982 Aug;5(1):61-72 PMID: 6981637

Article Info

Journal

Immunology

Abbr.

Immunology

ISSN

0019-2805

Published

1985-10-00

Pages

377-9

Language

English

Region

England

NLM ID

0374672

PMCID

PMC1453686

Subset

External Links

PubMed source PMC Full Text View journal details

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Susceptibility and HLA-B27 in post-dysenteric arthropathies.

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