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PMID: 39177925 Published · ppublish English Journal Article

Computational fluid dynamics simulating of the FDA benchmark blood pump with different coefficient sets and scaler shear stress models used in the power-law hemolysis model.

Onder A, Incebay O, Yapici R

Abstract

Hemolysis is the most important issue to consider in the design and optimization of blood-contacting devices. Although the use of Computational Fluid Dynamics (CFD) in hemolysis prediction studies provides convenience and has promising potential, it is an extremely challenging process. Hemolysis predictions with CFD depend on the mesh, implementation method, coefficient set, and scalar-shear-stress model. To this end, an attempt was made to find the combination that would provide the most accurate result in hemolysis prediction with the commonly cited power-law based hemolysis model. In the hemolysis predictions conducted using CFD on the Food and Drug Administration (FDA) benchmark blood pump, 3 different scalar-shear-stress models, and 5 different coefficient sets with the power-law based hemolysis model were used. Also, a mesh independence test based on hemolysis and pressure head was performed. The pressure head results of CFD simulations were compared with published pressure head of the FDA benchmark blood pump and a good agreement was observed. In addition, results of CFD-hemolysis predictions which are conducted with scalar-shear-stress model and coefficient set combinations were compared with experimental hemolysis data at three operating conditions such as 6-7 L/min flow rates at 3500 rpm rotational speeds and 6 L/min at 2500 rpm. One of the combinations of the scalar-shear-stress model and the coefficient set was found to be within the error limits of the experimental measurements, while all other combinations overestimated hemolysis.

Keywords
CFD Centrifugal blood pump Hemolysis Scalar shear stress
MeSH 主题词
Hemolysis Hydrodynamics Stress, Mechanical United States Food and Drug Administration Heart-Assist Devices/adverse effects United States Computer Simulation Humans Equipment Design Models, Cardiovascular
作者与单位
共 3 位作者,点击展开单位 / ORCID
Onder Ahmet ORCID
Technical Sciences Vocational School, Mechanical and Metal Technologies Department, Konya Technical University, Konya, Turkey. [email protected].
Incebay Omer
Faculty of Engineering and Natural Science, Mechanical Engineering Department, Konya Technical University, Konya, Turkey.
Yapici Rafet
Faculty of Engineering and Natural Science, Mechanical Engineering Department, Konya Technical University, Konya, Turkey.
Article Info
Journal
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs
Abbr.
J Artif Organs
ISSN
1619-0904
Corresponding email
Published
2025-06-00
电子出版
2024-00-23
页码
184-191
Language
English
Country/Region
Japan
NLM ID
9815648
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