Guanine nucleotides and Ca-dependent exocytosis. Studies on two adrenal cell preparations.

FEBS letters ·Vol. 189 ·No. 2 ·1985-09-23 ·Pages 345-9

Knight DE, Baker PF

Abstract

Exposure of 'leaky' adrenal medullary cells to GTP-y-S inhibits Ca-dependent exocytosis in bovine cells, but stimulates exocytosis in chicken cells. The inhibitory action on bovine cells persists in the presence of TPA suggesting that in this tissue an inhibitory GTP-binding protein may modulate the action of protein kinase C on exocytosis.

MeSH Terms

Adrenal Glands/cytology Animals Calcium/metabolism Cattle Chickens Diglycerides/pharmacology Exocytosis GTP-Binding Proteins/metabolism Guanine Nucleotides/metabolism Guanosine 5'-O-(3-Thiotriphosphate) Guanosine Triphosphate/analogs & derivatives,pharmacology Guanylyl Imidodiphosphate/pharmacology Tetradecanoylphorbol Acetate/pharmacology Thionucleotides/pharmacology

Chemicals

Diglycerides Guanine Nucleotides Thionucleotides Guanylyl Imidodiphosphate Guanosine 5'-O-(3-Thiotriphosphate) Guanosine Triphosphate 1-oleoyl-2-acetylglycerol GTP-Binding Proteins Tetradecanoylphorbol Acetate Calcium

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Knight D E

Baker P F

Article Info

Journal

FEBS letters

Abbr.

FEBS Lett

ISSN

0014-5793

DOI

10.1016/0014-5793(85)81053-x

Published

1985-09-23

Pages

345-9

Language

English

Region

England

NLM ID

0155157

Subset

External Links

PubMed source DOI: 10.1016/0014-5793(85)81053-x View journal details

Analysis Services

Guanine nucleotides and Ca-dependent exocytosis. Studies on two adrenal cell preparations.

Contact

WeChat Official Account