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PMID: 3937000 Published · ppublish English Comparative Study Journal Article

The control of puberty in the dietary restricted female rat.

Mechanisms of ageing and development ·Vol. 32 ·No. 2-3 ·1985-11-00 ·Pages 179-91

Holehan AM, Merry BJ

Abstract

Food intake, body weight and serum LH, FSH, progesterone and oestradiol-17 beta were monitored from weaning to puberty in fully fed females housed in groups of four or individually and in females individually housed and dietary restricted. Restriction of food intake from weaning delayed the onset of puberty (34-39 days fully fed, 63-189 days dietary restricted) which was achieved at the same body weight as in the fully fed females. Individual housing of fully fed rats resulted in a significant increase in relative and absolute food intake (but not body weight) and a decrease in serum FSH when compared to group housed fully fed animals. Serum FSH and progesterone were significantly decreased in restricted females and serum oestradiol-17 beta significantly increased.

MeSH Terms
Animals Body Weight Diet, Reducing Energy Intake Estradiol/blood Estrus Female Follicle Stimulating Hormone/blood Luteinizing Hormone/blood Progesterone/blood Rats Rats, Inbred Strains Sexual Maturation Vagina/physiology
Chemicals
Progesterone Estradiol Luteinizing Hormone Follicle Stimulating Hormone
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Holehan A M
Merry B J
Article Info
Journal
Mechanisms of ageing and development
Abbr.
Mech Ageing Dev
ISSN
0047-6374
Published
1985-11-00
Pages
179-91
Language
English
Region
Ireland
NLM ID
0347227
Subset
IM
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