Home LiteratureArticle Details
PMID: 3943910 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Ability of oral bacteria to degrade fibronectin.

Infection and immunity ·Vol. 51 ·No. 2 ·1986-02-00 ·Pages 707-11

Wikström M, Linde A

Abstract

The fibronectin-degrading ability of 116, mainly oral, strains was assayed by using plasma-derived fibronectin adsorbed to a polystyrene surface. Ability to degrade fibronectin was revealed in strains of Bacteroides gingivalis, Bacteroides intermedius, Bacteroides loeschii, Staphylococcus aureus, Staphylococcus epidermidis, Peptococcus prevotii, Clostridium sporogenes, and Propionibacterium acnes. The fibronectinolytic activity of subgingival bacteriological samples was found to be related to the presence of B. gingivalis and B. intermedius. In addition, strains of the nonoral Bacteroides species B. asaccharolyticus and B. fragilis showed fibronectin-degrading ability. No such ability was detected in the oral strains tested of Streptococcus, Veillonella, Actinomyces, Lactobacillus, Actinobacillus, Capnocytophaga, Fusobacterium, or Haemophilus species.

MeSH Terms
Bacteria/metabolism Bacteroides/metabolism Fibronectins/metabolism Humans Mouth/microbiology
Chemicals
Fibronectins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Wikström M
Linde A
References (22)
22 references, click to expand
  1. Role of adherence in the pathogenesis of Pseudomonas aeruginosa lung infection in cystic fibrosis patients.
    Infect Immun. 1980 Dec;30(3):694-9 PMID: 7014444
  2. Occurrence and nature of bacterial IgA proteases.
    Ann N Y Acad Sci. 1983 Jun 30;409:612-24 PMID: 6347000
  3. Enzymatic characterization of some oral and nonoral gram-negative bacteria with the API ZYM system.
    J Clin Microbiol. 1981 Sep;14(3):288-94 PMID: 7026598
  4. Role of salivary protease activity in adherence of gram-negative bacilli to mammalian buccal epithelial cells in vivo.
    J Clin Invest. 1981 Dec;68(6):1435-40 PMID: 6798070
  5. Degradation of immunoglobulins A2, A2, and G by suspected principal periodontal pathogens.
    Infect Immun. 1981 Dec;34(3):757-65 PMID: 7037640
  6. Determination of proteolytic activity: a sensitive and simple assay utilizing substrate adsorbed to a plastic surface and radial diffusion in gel.
    Anal Biochem. 1981 Dec;118(2):240-6 PMID: 6802022
  7. Fibronectins: multifunctional modular glycoproteins.
    J Cell Biol. 1982 Nov;95(2 Pt 1):369-77 PMID: 6128348
  8. Adherence of group A streptococci to fibronectin on oral epithelial cells.
    Infect Immun. 1983 Jan;39(1):275-9 PMID: 6337097
  9. Detection of microbial proteolytic activity by a cultivation plate assay in which different proteins adsorbed to a hydrophobic surface are used as substrates.
    Appl Environ Microbiol. 1983 Feb;45(2):393-400 PMID: 6338825
  10. Vibrio cholerae hemagglutinin/lectin/protease hydrolyzes fibronectin and ovomucin: F.M. Burnet revisited.
    Proc Natl Acad Sci U S A. 1983 Feb;80(4):1092-5 PMID: 6341990
  11. Adherence of streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa to fibronectin-coated and uncoated epithelial cells.
    Infect Immun. 1983 Sep;41(3):1261-8 PMID: 6411621
  12. API ZYM system for identification of Bacteroides spp., Capnocytophaga spp., and spirochetes of oral origin.
    J Clin Microbiol. 1982 Jan;15(1):97-102 PMID: 6764781
  13. Degradation of the human proteinase inhibitors alpha-1-antitrypsin and alpha-2-macroglobulin by Bacteroides gingivalis.
    Infect Immun. 1984 Feb;43(2):644-8 PMID: 6198282
  14. Degradation of human immunoglobulins by proteases from Streptococcus pneumoniae obtained from various human sources.
    Infect Immun. 1984 Apr;44(1):33-7 PMID: 6368393
  15. Ultrastructural localization of fibronectin in duct cells of human minor salivary glands and its immunochemical detection in minor salivary gland secretion.
    Arch Oral Biol. 1984;29(11):921-5 PMID: 6393926
  16. [Immunelectrophoretic studies of the action of Bacteroides, Fusobacterium, Leptotrichia, and Sphaerophorus species on human plasma proteins].
    Zentralbl Bakteriol Orig. 1971;216(1):96-113 PMID: 4251689
  17. Physiological differentiation of viridans streptococci.
    J Clin Microbiol. 1977 Feb;5(2):184-201 PMID: 845245
  18. Binding of human fibronectin to group A, C, and G streptococci.
    Infect Immun. 1983 Apr;40(1):29-34 PMID: 6299959
  19. Correlation of virulence and collagenolytic activity in Entamoeba histolytica.
    Infect Immun. 1983 Feb;39(2):528-31 PMID: 6299942
  20. Interaction of human plasma fibronectin with cariogenic and non-cariogenic oral streptococci.
    Infect Immun. 1983 Jul;41(1):162-8 PMID: 6862625
  21. Fibrinogenolytic and fibrinolytic activity in oral microorganisms.
    J Clin Microbiol. 1983 May;17(5):759-67 PMID: 6345573
  22. Role of fibronectin in the prevention of adherence of Pseudomonas aeruginosa to buccal cells.
    J Infect Dis. 1981 Jun;143(6):784-90 PMID: 6788858
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.51.2.707-711.1986
Published
1986-02-00
Pages
707-11
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC262417
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.51.2.707-711.1986 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2