Arteriovenous malformations of the brain: natural history in unoperated patients.

Journal of neurology, neurosurgery, and psychiatry ·Vol. 49 ·No. 1 ·1986-01-00 ·Pages 1-10

Crawford PM, West CR, Chadwick DW, Shaw MD

Abstract

Two-hundred and seventeen patients from a total population of 343 patients with arteriovenous malformations, were managed without surgery. Follow up was for a mean of 10.4 years. Using life survival analyses, there was a 42% risk of haemorrhage, 29% risk of death, 18% risk of epilepsy and a 27% risk of having a neurological handicap by 20 years after diagnosis in unoperated patients.

MeSH Terms

Adolescent Adult Aged Child Child, Preschool Epilepsy/etiology Follow-Up Studies Humans Hydrocephalus/etiology Infant Intracranial Arteriovenous Malformations/complications,diagnosis,surgery Middle Aged Retrospective Studies Risk Subarachnoid Hemorrhage/etiology Syndrome

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Crawford P M

West C R

Chadwick D W

Shaw M D

References (14)

14 references, click to expand

Report on the cooperative study of intracranial aneurysms and subarachnoid hemorrhage. Section VI. Arteriovenous malformations. An analysis of 545 cases of cranio-cerebral arteriovenous malformations and fistulae reported to the cooperative study.
J Neurosurg. 1966 Oct;25(4):467-90 PMID: 5925721
Arteriovenous malformations.
J Neurosurg. 1970 May;32(5):503-11 PMID: 5438092
Arteriovenous malformations of the brain. Prognosis without operation.
Acta Neurochir (Wien). 1970;22(2):125-8 PMID: 5521225
Subarachnoid hemorrhage due to ruptured aneurysms. A simple method of estimating prognosis.
Arch Neurol. 1972 Oct;27(4):273-84 PMID: 5055341
Arteriovenous malformations of the brain. A long-term clinical study.
J Neurosurg. 1972 Nov;37(5):562-70 PMID: 5076373
Assessment of outcome after severe brain damage.
Lancet. 1975 Mar 1;1(7905):480-4 PMID: 46957
Signs and symptoms of supratentorial arteriovenous aneurysms.
J Neurosurg. 1958 Sep;15(5):471-80 PMID: 13576190
The long-term prognosis in untreated cerebral aneurysms: I. The incidence of late hemorrhage in cerebral aneurysm: a 10-year evaluation of 364 patients.
Ann Neurol. 1977 Apr;1(4):358-70 PMID: 617253
Arteriovenous malformations. Summary of 100 consecutive supratentorial cases.
J Neurosurg. 1980 Sep;53(3):285-99 PMID: 7420143
Intracranial arteriovenous malformations. Conservative and surgical treatment.
J Neurosurg. 1980 Aug;53(2):149-52 PMID: 6159458
Bleeding from cerebral arteriovenous malformations as part of their natural history.
J Neurosurg. 1983 Mar;58(3):331-7 PMID: 6827317
Cerebral arteriovenous malformations. Comparative results of surgical vs conservative treatment in 112 cases.
J Neurosurg Sci. 1983 Jul-Sep;27(3):203-10 PMID: 6663354
Natural history of arteriovenous malformations of the brain: a clinical study.
Neurosurgery. 1984 Nov;15(5):658-62 PMID: 6504280
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples.
Br J Cancer. 1977 Jan;35(1):1-39 PMID: 831755

Article Info

Journal

Journal of neurology, neurosurgery, and psychiatry

Abbr.

J Neurol Neurosurg Psychiatry

ISSN

0022-3050

DOI

10.1136/jnnp.49.1.1

Published

1986-01-00

Pages

1-10

Language

English

Region

England

NLM ID

2985191R

PMCID

PMC1028639

Subset

External Links

PubMed source DOI: 10.1136/jnnp.49.1.1 PMC Full Text View journal details

Analysis Services

Arteriovenous malformations of the brain: natural history in unoperated patients.

Contact

WeChat Official Account